Peptide

How Do Peptides Support The Immune System?

Peptides are chains of amino acids. Your body makes peptides, but they can also be made in a lab. Lab-created peptides mimic the peptides made by your body and are often used in supplements.

Each type of peptide has a different role in your body. Benefits of peptides include:

  • Anti-aging
  • Improving the skin barrier
  • Muscle growth
  • Weight loss

Peptides are also essential to support immune system function.

The importance of a healthy immune system

Your immune system is an extensive network of chemicals, organs, proteins (antibodies), and white blood cells. This system functions to protect you from bacteria, fungi, parasites, and viruses that cause diseases, illnesses, and infections.

White blood cells serve as an army against harmful bacteria and viruses. They search for, attack, and destroy germs to keep you healthy. There are many different types of white blood cells. Some white blood cells circulate in your bloodstream and throughout your body, while other types reside in a particular tissue and wait to be called into action.

Lymph nodes are small glands that are part of your lymphatic system which filter and destroy germs. There are hundreds of lymph nodes all over your body, including in your armpits, groin, and neck. The immune cells in your lymph nodes analyze the foreign invaders brought into your body and then activate, replicate, and send lymphocytes (white blood cells) to fight off each invader. When your body is fighting an infection, your lymph nodes may become swollen and tender.

Your spleen stores white blood cells, filters your blood, and destroys old and damaged red blood cells.

Tonsils and adenoids are located in your throat and nasal passage, which gives them the ability to trap foreign invaders as soon as they enter your body. Your tonsils and adenoids also contain immune cells that produce antibodies that protect you from throat and lung infections.

The thymus is a small organ in your upper chest beneath your breastbone. Its job is to help develop a certain type of white blood cell that learns to recognize and remember an invader so your body can attack the invader more quickly the next time it is encountered.

Bone marrow consists of stem cells in the spongy center of your bones. Bone marrow develops into plasma cells, red blood cells, a variety of white blood cells, and other types of immune cells. Your bone marrow produces billions of new blood cells every day and releases them into your bloodstream.

The skin can destroy germs before they enter your body because your skin produces oils and immune system cells. Your digestive, reproductive, respiratory, and urinary tracts are lined with mucus membranes that lubricate and moisten surfaces.

Tiny hairs in your nose and the mucus in your respiratory tract trap germs, and hair-like structures called cilia move the germs out of your airways.

Vaginal secretions and enzymes in your mucus membranes, saliva, sweat, and tears also destroy germs.

Stomach acid kills many types of bacteria, and there are beneficial bacteria in your intestines that kill harmful bacteria.

Peptides and immune function

Peptides can help the immune function of the body in several ways. Here are some examples

Antimicrobial properties

Many peptides have antimicrobial properties, meaning that they can help defend against invading pathogens by destroying or inhibiting their growth.

Regenerating tissues

Peptides like thymosin beta four and GHK-Cu have been shown to promote tissue regeneration, which can be helpful in repairing damage caused by infections or injuries.

Immunomodulation

Some peptides can modulate the immune system’s response to pathogens, such as increasing the production of cytokines and other signaling molecules that activate immune cells to fight off infections.

Anti-inflammatory effects

Peptides such as LL-37 have powerful anti-inflammatory effects, which can help reduce tissue damage caused by inflammation during infection and reduce systemic inflammation overall.

As you can see, peptides play a crucial role in supporting the body’s immune function. There is still ongoing research on understanding more about peptides’ mechanisms of action and ways they modulate our immune system response during various infections and diseases.

Types of peptides involved in immune function

Some peptides have been shown to support the immune system by impacting its cells, acting as antimicrobial agents, as well as improving and modulating its response to foreign pathogens.

Here are some of the peptides that have demonstrated benefits for the immune system:

This peptide is produced naturally in the body’s white blood cells and has demonstrated potent antimicrobial properties by inhibiting several bacterial and viral strains’ growth.

These peptides play a significant role in regulating inflammation within the immune system and reducing autoimmune-related conditions by lowering inflammatory cytokine levels.

This peptide has strong antioxidant activity while boosting immunity against common infections such as colds or flu due to its antiviral properties.

This peptide helps modulate T-cell activity and support natural killer cells’ function, two essential components of immune defense against cancer cells or viruses.

These peptides are natural antimicrobial peptides found in various tissues throughout the body, including skin and mucous membranes. They work by killing bacteria that try to bind with these tissues.

CJC-1295 and ipamorelin are two different peptides that are often combined together. Each of these peptides is quite potent on its own, and their effects are maximized when taken together.

  • CJC-1295 is a synthetic peptide originally that has been found to improve athletic performance. It increases protein synthesis and boosts the body’s insulin-like growth factor levels, which stimulates muscle tissue growth.
  • Ipamorelin is a hormone secretagogue that stimulates the production of hormones in the pituitary gland and helps them enter the bloodstream. This peptide may help improve cognitive skills and memory, increase growth and muscle development, regulate internal body temperature, and relieve pain.

In addition to increasing muscle growth, the growth hormone levels that CJC-1295 and ipamorelin increase may also strengthen the immune system and help your body fight against illness-causing invaders like bacteria and viruses.

Growth hormone is essential for the function and health of your immune system because this hormone affects the thymus gland, which produces T cells that help rid your body of cells that are infected with viruses and even certain types of cancer. In other words, the more growth hormones you have in your body, the more T cells you will have, which can support a stronger immune system.

BPC-157

BPC-157 (Body Protecting Compound-157) is a peptide with anti-inflammatory, cytoprotective, and endothelial-protective effects. This peptide can be used to help treat viral infections such as COVID-19 by addressing how the virus affects the brain, heart, liver, and lungs.

BPC-157-activated endothelial nitric oxide synthase (eNOS) causes the release of nitric oxide (NO), which repairs tissue, improves vascular health and immune response, and reduces inflammation and critical levels of COVID-19. BPC-157 helps improve biochemical and clinical parameters, reduces cytokine derailment and organ failure caused by COVID-19, and restricts the virus from multiplying.

In severe cases, COVID-19 can lead to NO deficiency and the loss of eNOS activity due to hypertension and thrombus formation. BPC-157 helps in the early stages of COVID-19 by interacting with eNOS and NO, decreasing thrombosis and lowering viral load.

BPC-157 also has many potential protective effects on the heart and lungs, including but not limited to the following:

  • Counteracting lung lesions
  • Counteracting right heart failure by acute thrombotic coronary occlusion
  • Preventing and resolving inferior cava vein hypertension
  • Preventing pulmonary interstitial edema
  • Reducing lymphocyte count and capillary congestion
  • Reducing the duration of arrhythmias during hypoxia (when there is not enough oxygen in the tissues to maintain homeostasis) and reoxygenation

In addition to being used to help treat COVID-19 and protect the health of your heart and lungs, BPC-157 has also been shown in studies of rodents to protect the liver by healing bile duct ligation, gastrointestinal lesions, hepatic encephalopathy, and liver lesions.
BPC-157 also has neuroprotective effects and may reduce brain-related complications from COVID-19, including brain inflammation, encephalopathies, peripheral nerve damage, and strokes.

Overall, several types of peptides can help bolster our innate immune system response, promoting antibacterial or antiviral activity while modulating overactive autoimmune responses caused by certain diseases like lupus or rheumatoid arthritis. However, all new potential therapies must undergo rigorous testing via clinical trials before becoming generally implemented treatments available for people to use daily.

Clinical uses and studies

Because they have reproducible chemical synthesis, rapid tissue penetration, low immunogenicity, and fast blood clearance, peptides are ideal for clinical use in disease diagnostics and therapeutics for a wide variety of conditions.

A 2015 study revealed the effects of three types of peptide-based chemotherapy on various types of cancer, including breast cancer, colorectal cancer (CRC), gastric cancer, lung cancer, pancreatic cancer (PC), and prostate cancer. The three types of peptide-based chemotherapy are peptide-alone therapy, peptide vaccines, and peptide-conjugated nanomaterials.

How to Incorporate Peptides Into Training for Optimal Results

In order to safely and effectively incorporate peptides into your training regimen, it is important to work with a healthcare professional who specializes in peptide therapy. They can help determine the peptides that are best suited for your individual needs, as well as guide you on dosing and delivery methods.

Dosing and delivery are crucial components to consider when incorporating peptides into your training regimen. It is important to understand the recommended dosage for each specific peptide and to adhere to these guidelines for optimal results. Additionally, peptides can be delivered in a variety of ways, including injection, sublingual, nasal spray, and topical creams. The healthcare professional can help you determine the most effective delivery method for your specific needs.

It is also important to remember that incorporating peptides into your training regimen should not replace proper nutrition, hydration, and exercise. Peptides should be viewed as a supplemental tool to enhance your athletic performance, not a replacement for healthy habits.

  • Peptide-alone therapy can enhance the immune system’s ability to kill tumor cells.
  • Peptide-based vaccines have been used in severe cancers to improve overall survival rates.
  • Peptide-conjugated nanomaterials enhance drug delivery and sensitivity.

A 1994 study found that the peptide p277 can reverse autoimmune diabetes in non-obese diabetic (NOD) mice.

glass bottle of peptide

Autoimmune diabetes that NOD mice have is similar to insulin-dependent diabetes Mellitus (IDDM) in humans.

Future implications

It is likely that cell-penetrating peptides (CPPs), multifunctional peptides, and peptide drug conjugates (PDC) are the future of peptide therapy. CPPs promote transdermal absorption of biomolecular drugs, which makes them greatly valuable in cosmetic fields, targeted formulations, and transdermal drug delivery formulations.

Multifunctional peptides improve the efficacy and druggability of indications and are being studied by large pharmaceutical companies such as Eli Lilly, Johnson and Johnson, Merick, Novo Nordisk, Sanofi, and others. PDCs enhance drug targeting, improve effectiveness, and reduce adverse effects because they combine a cell-targeting peptide with a drug molecule.

Last words

Your immune system protects your body from infection by bacteria, fungi, viruses, and other foreign pathogens that can harm you. Peptides can boost your immune system and promote your overall health.

There are several peptides that support immune system function, including:

  • Beta defensins
  • Glutathione peptides
  • LL-37
  • Melanocortin receptor peptides
  • Thymosin alpha 1

Talk to your doctor about using peptide therapy to boost your immune system or treat illnesses. They will know which peptides are right for your individual situation.

Revitalize With Peptide Therapy

Peptides are short chains of amino acids that serve as building blocks for proteins and play crucial roles in many biological functions. Combat age-related decline of peptides in your body with our scientifically formulated peptides, which offer a range of health benefits:

SERMORELIN - Boost lean muscle & reduce fat.

GHK-CU - Promote skin rejuvenation & firmness.

PT-141 - Intensify sexual desire & function.

Order today and receive your peptides at home, where you can self-administer your treatments with ease.

Peptide Shots - Frequently Asked Questions

What is included in our peptides injections?

There are many different peptide injections that we offer as part of a peptide therapy including Sermorelin, GHK-CU and PT-141.

What is SERMORELIN?

Sermorelin is a synthetic form of GHRH (growth hormone-releasing hormone) which controls the hGH (human growth hormone) and it’s recommended to people who have low levels of hGH. 

How do peptides improve your sleep?

Serotonin is a neurotransmitter present in the brain that releases chemicals as messages to your brain and body that it is time to go to sleep. Some peptides can interact with serotonin. Serotonin regulation issues can definitely interfere with a person's ability to have a good night's sleep.

Sermorelin is recognized for their potency as peptides that enhance sleep.

How do peptides improve immune health?

The immune response can be either blocked or stimulated to produce tolerance using peptides and peptidomimetics as immunomodulating agents.

Read more: Peptide Shots FAQ