vial with blue pills inside

Nicotinamide Riboside: A Powerful NAD Booster

friends sitting on the ground happy person sunset forest

Nicotinamide adenine dinucleotide (NAD), a vital coenzyme found in all living cells, plays a crucial role in:

NAD levels are known to decrease with age, which can lead to aging-related diseases. Fortunately, a powerful solution to maintain NAD levels is nicotinamide riboside (NR). NR is a form of vitamin B3 converted into NAD in the body and is available in supplement form to boost NAD levels and support healthy aging.

NAD's Role in Your Metabolism

NAD works on mitochondria and increases the length of telomeres, which are the protective caps located at the ends of chromosomes that become shorter as the body ages. NAD increases the activity of SIRT1 and PARP 1 proteins, which are linked with a slower rate of aging and influencing DNA repair respectively. – source

What is nicotinamide riboside?

Nicotinamide Riboside (NR) is a model of Vitamin B3, often called niacin or nicotinic acid. NR is similar to other forms of Vitamin B3, such as nicotinic acid and niacinamide, but its chemical structure is slightly different.

NR is known for increasing levels of nicotinamide adenine dinucleotide (NAD), a key molecule in the body’s energy production and metabolism. NAD levels naturally decline with age, and low NAD levels have contributed to various chronic diseases. As such, NR has become popular as a health supplement among those looking to boost their NAD levels and support overall health.

The science behind NR’s NAD-boosting properties

Nicotinamide riboside (NR), also known as vitamin B3, can significantly boost cell nicotinamide adenine dinucleotide (NAD+) levels.3 NAD+ is a critical coenzyme in all living cells and is essential for many cellular functions.

healthcare professional looking at a tablet

NR can effectively increase NAD+ levels in cells by directly converting NR to NAD+ and indirectly activating enzymes called sirtuins. Sirtuins are responsible for various essential functions, such as regulating metabolic processes, DNA repair, and aging. Research suggests that NR is a powerful NAD+ booster that could support healthy aging and promote overall well-being.

Potential health benefits of NR

Nicotinamide Riboside (NR), or vitamin B3 can be found in small amounts in milk, brewers’ yeast, and certain other foods. It has recently become available as a dietary supplement.

NR’s most notable potential benefit is its ability to increase the body’s levels of NAD+.

A female doctor prescribing something to her patient.

It is a critical coenzyme found in all living cells that play an essential role in energy metabolism, making NR a promising supplement for:

  • cognitive function
  • healthy aging

A few of the potential health benefits of NR include:

  • Cardiovascular Health: NR can help reduce inflammation and oxidative stress in the cardiovascular system, significant contributors to heart disease. NR may also improve endothelial function, which helps maintain healthy blood vessels and promote healthy blood flow.
  • Insulin Sensitivity: NR can help increase insulin sensitivity, which can help decrease the chances of developing metabolic disorders such as type 2 diabetes. NR can also help improve glycemic control, crucial for maintaining healthy blood sugar levels.
  • Cognitive Function: NR may stimulate cognitive function and reduce the risk of age-related cognitive decline. NR acts as an antioxidant in the brain, helping to protect against free radical damage.
  • Energy Metabolism: By increasing the body’s levels of NAD+, NR may help improve energy metabolism and reduce fatigue and could benefit people with chronic fatigue syndrome or conditions causing excessive fatigue.
  • Aging: NAD+ plays a vital role in DNA repair and other processes associated with aging. Increasing NAD+ levels through NR supplementation may help slow aging and promote healthy longevity.

While more research is needed to confirm these potential benefits, NR is a promising supplement for improving overall health and well-being.

Potential side effects of nicotinamide riboside

Despite the potential health benefits of Nicotinamide Riboside (NR), it is vital to be aware of the possible side effects that may arise from taking this supplement. Common side effects of NR include:

woman heaving a headache
  • headaches
  • nausea
  • fatigue
  • dizziness

Allergic reactions are also possible, as is flushing.

  • Headaches: May range from mild to severe. If you experience a headache after taking NR, drink plenty of fluids and rest until the symptoms pass.
  • Nausea: If you experience nausea after taking NR, you should stop taking the supplement and consult your doctor or healthcare provider.
  • Fatigue: May range from mild to severe. If you experience fatigue after taking NR, getting plenty of rest and avoiding activities requiring physical exertion is recommended.
  • Dizziness: If you experience dizziness after taking NR, you should stop taking the supplement and consult your doctor or healthcare provider.
  • Allergic reactions: Symptoms of an allergic reaction include swelling of the face, itching, rash, hives, difficulty breathing, or swelling of the face, lips, tongue, or throat. If you experience these symptoms after taking NR, seek immediate medical attention.
  • Flushing: occurs when the body’s blood vessels dilate, resulting in redness and warmth in the face, neck, and chest. It is important to remember that while flushing is not typically harmful, it is crucial to seek medical attention if the symptoms become more severe or do not go away after a few minutes.

It is always important to speak to your doctor before taking any supplements, including NR, to ensure they are safe for you and will not interact with any other medications or supplements you are currently taking.

How to take NR

When taking nicotinamide riboside (NR), knowing the recommended dosage and administration methods is imperative. You should consult your doctor before taking NR to determine the best dose for your needs.

Be conscious of any potential interactions with other supplements and medications you may be taking. While there are no known interactions between NR and other supplements or medications, as a precaution, it’s still a good idea to consult with your healthcare professional before taking NR to ensure that NR will not interfere with your other medications or supplements. Additionally, they can advise you on any potential side effects or drug interactions and help ensure that taking NR is safe for you.

Final thoughts

Nicotinamide riboside (NR) is a novel compound that has gained attention for its potential as a powerful NAD booster. NR increases NAD levels in the body, boosting energy production, cellular protection, and enhanced mitochondrial function.

However, additional research is required to understand NR’s safety and effectiveness fully. Always consult a healthcare professional before beginning new treatments or regimens, including NR, to ensure that you are taking the correct dose and that it won’t interact with any medications or supplements you are already taking.

Take the First Step towards Better Health with NAD Therapy

Take control of your health and address your biggest health concerns with NAD therapy. Consult with a trusted medical professional today to explore the potential benefits of NAD and find personalized solutions for your unique needs.

  • Convenience
  • Comfort
  • Privacy
  • Personalized care
  • Flexible scheduling

Transform your health with NAD therapy and experience the life-changing benefits of personalized treatment tailored to your unique needs.

NAD - Frequently Asked Questions

What is NAD?

NAD is a coenzyme that is naturally produced by the body and is essential for various physiological processes, including energy production and DNA repair. It is found in all living cells and plays a critical role in many of the body's metabolic processes. NAD is a dinucleotide, which means that it consists of two nucleotides joined together. It is made up of two molecules: nicotinamide and adenine, which are joined together by a phosphate group.

NAD is involved in a wide range of biological processes, including the metabolism of carbohydrates, proteins, and fats, and is essential for the proper functioning of the body's cells and tissues.

What can I expect during a NAD IV treatment?

Our nurse will arrive at your location of choice with all the equipment necessary for the appointment. They will then administer the IV into your arm and stay with you to monitor the treatment and answer any questions you may have.

Our NAD IV treatments generally last 3 - 4 hours per session. You can sit back, watch a movie or a favorite show, browse social media, or even work while the treatment is in progress.

What sets Drip Hydration apart from other NAD IV treatment providers?

Drip Hydration brings appointments directly to you whether you are at home, at a hotel, or at the office. We make getting at home NAD IV treatments easy and convenient, saving you the time and hassle of sitting in traffic or waiting in a clinic.

Is NAD right for me?

You don’t have to wait until you are experiencing a medical condition to enjoy the benefits of NAD IV therapy. NAD plays a role in hundreds of chemical functions throughout your body. This versatile treatment helps promote whole-body wellness and can help your body maintain optimal performance over time.

Is IV therapy FDA approved?

IV therapy in general is FDA approved. Our nurses are overseen by our Medical Director, Abe Malkin, and every nurse is registered and certified per state standards.

Is NAD safe?

NAD is considered a dietary supplement, not a drug. The FDA does not currently evaluate dietary supplements in their current regulations. However, NAD is well-tolerated, meaning that there are rarely side effects.

How long do IV treatments take?

Our IV NAD treatments take between 3 - 4 hours to administer per session. The number of sessions vary by individual and will be determined during your initial consultation.

Does NAD help battle aging?

Some studies have suggested that NAD may have anti-aging effects by helping to support the production of enzymes that are involved in DNA repair and maintenance, which are essential for maintaining healthy cells and tissues. Additionally, NAD may support the production of enzymes that are involved in the body's natural detoxification processes, which can help to reduce the effects of oxidative stress and support healthy aging. 

Does NAD Improve metabolic function?

Some studies have suggested that NAD may support healthy metabolism by helping to regulate the body's energy production and utilization, and may also support the production of enzymes that are involved in various metabolic processes. Additionally, NAD may support the body's natural detoxification processes, which are important for maintaining overall health and wellness.

How often can I get an NAD treatment?

NAD IV treatments are most effective when used over time. You can get treatments several times per month unless you are otherwise advised during your initial consultation.

What can I expect to feel after a NAD IV drip?

Following a NAD IV drip, most patients feel more energetic, clearer-headed, and focused. Regular treatments may improve these effects over time.

Is there any downtime or recovery after a NAD drip?

Not at all! You can resume your normal activities immediately after your appointment. Where do you deliver NAD IV treatments? Drip Hydration delivers NAD IV treatments anywhere within our service areas, which you can find on our service area pages. That said, we recommend choosing a comfortable place for NAD treatments since this type of IV takes 3 - 4 hours per appointment.

How is IV NAD better than an oral NAD supplement?

IV NAD is delivered directly into your bloodstream, where it becomes available to your cells for immediate use. Because NAD bypasses the digestive and metabolic systems, you can expect a 100% absorption rate for maximum effect and minimal waste. Oral NAD supplements, on the other hand, must pass through your digestive system, where they are partly metabolized before your body has access to orally given NAD.

What is the difference between a NAD IV and a vitamin drip?

There are two main differences between a NAD IV and a Vitamin Drip: duration and ingredients. NAD IVs generally take 3 - 4 hours to administer per session while vitamin drips take 30 - 45 minutes. Our vitamin drips are specially blended to improve a variety of symptoms and ailments. Our NAD+ Boost treatments contains vitamins that can help make this IV more effective with longer-lasting effects.

Do I need any special supplies for my NAD IV appointment?

No, you do not need any special supplies. Our nurse will bring everything needed for the appointment.

Does NAD improve brain health and function?

NAD is believed to have potential benefits for brain health and function, although more research is needed to fully understand its effects. Some studies have suggested that NAD may have neuroprotective effects, meaning that it may help to protect the brain from damage and support healthy brain function. Additionally, NAD may support the production of neurotransmitters, which are chemicals that help to transmit signals between the brain's cells, and may help to improve cognitive function and memory.

NAD Injection Therapy

What are the benefits of NAD Injection Therapy?

NAD injection therapy is believed to have several potential benefits, including improving energy levels, supporting cognitive function, reducing inflammation, and supporting the body's natural detoxification processes. Additionally, NAD injection therapy is often used in combination with other treatments, such as IV vitamin therapy, to support the body's natural recovery processes and improve overall health and wellness.

What is the difference between NAD injection vs NAD IV therapy?

The main difference between NAD injection and NAD IV therapy is the method of delivery. NAD injection involves injecting NAD directly into the bloodstream using a syringe, while NAD IV therapy involves infusing NAD into the bloodstream through a small tube that is inserted into a vein.

What is the difference between NAD injections and NAD supplements?

The main difference between NAD injections and NAD supplements is the method of delivery. NAD injections involve injecting NAD directly into the bloodstream using a syringe, while NAD supplements are taken orally in the form of pills or capsules.

How to best self-administer a NAD injection?

When administering the injection, it is important to use a clean, sterile needle and syringe, and to inject the NAD into a vein using a slow, steady motion. It is also important to properly dispose of the used needles and syringes to avoid the risk of injury or infection. It is also important to carefully follow the instructions provided by the healthcare professional and the manufacturer of the NAD injection, including proper storage and handling of the injection and any necessary preparation steps.

NAD+ Nasal Spray

What are the benefits of NAD+ nasal spray?

NAD+ nasal spray is believed to have several potential benefits, including improving energy levels, supporting cognitive function, reducing inflammation, and supporting the body's natural detoxification processes.

What is the difference between NAD injection and NAD+ nasal spray?

The main difference between NAD injection and NAD+ nasal spray is the method of delivery. NAD injection involves injecting NAD directly into the bloodstream using a syringe, while NAD+ nasal spray involves delivering NAD directly into the bloodstream through the nose.

What is the difference between NAD+ nasal spray and NAD supplements?

The primary distinction between NAD+ nasal spray and NAD supplements is the route of administration. NAD+ nasal spray delivers NAD directly into the bloodstream via the nose, whereas NAD supplements are taken orally as tablets or capsules.

How often can I use the NAD+ nasal spray?

The frequency of NAD+ nasal spray use will depend on the specific product and the individual's needs and preferences. It is important to consult with a healthcare professional to determine the appropriate frequency of NAD+ nasal spray use, as well as any potential risks or side effects. In general, NAD+ nasal spray can be used daily or as needed, depending on the individual's goals and needs. It is also important to carefully follow the instructions provided by the healthcare professional and the manufacturer of the NAD+ nasal spray, including any recommended dosing guidelines and precautions.

What can I expect to feel after using the NAD+ nasal spray?

The effects of NAD+ nasal spray may vary depending on the individual and their unique physiology and health needs. In general, people may experience improved energy levels, cognitive function, and overall health and wellness after using NAD+ nasal spray. Additionally, NAD+ nasal spray may help to support the body's natural recovery processes and reduce the symptoms of conditions such as chronic fatigue syndrome, fibromyalgia, and addiction.

References

[1] Schultz MB. - Why NAD(+) Declines during Aging: It's Destroyed.;

[3] Mehmel M. - Nicotinamide Riboside-The Current State of Research and Therapeutic Uses.;