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With things moving at such a fast pace, there has been an increased need for convenient health solutions. Thanks to advances in medical technology, the quantity of health solutions has exploded in recent years. Of the treatments currently available, many people are taking the time to research the effectiveness of peptides and their ability to improve different aspects of their health.

Peptides are short chains of amino acids, and due to their capacity to interact with and control a variety of biological processes, they have the potential to be used in a wide variety of therapeutic applications.

Peptide Therapy

From combating aging to boosting muscle development and recovery and more, peptide treatments may help you achieve a wide range of health goals. Our peptide treatments are delivered to your doorstep and self-administered in the comfort of your home.

GHK-Cu | PT-141 | Sermorelin

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In recent years, peptides have had a meteoric rise in popularity, particularly in the fields of medicine, the beauty industry, and the fitness industry. To help you understand the benefits of various peptides, we have compiled this comprehensive guide to some of the most promising options.

LL-37 is an antimicrobial peptide from the cathelicidin family.

It is predominantly produced by immune and epithelial cells in response to infection or inflammation. LL-37 has been shown to potentially have potent antibacterial and anti-inflammatory properties, supporting the body in combating a variety of illnesses such as bacteria, viruses, and fungi. 

Beta-defensins are an antimicrobial peptide family that plays critical roles in the immune system.

They are largely produced by epithelial cells and aid in the body’s defense against a variety of pathogens, such as bacteria, viruses, and fungi. Beta-defensins act by compromising pathogen membrane integrity, resulting in their destruction.

They also possess immune control properties, helping to regulate the immune system to respond properly and reduce inflammation.

Thymosin alpha 1 is a peptide with immune system-boosting properties. 

It plays an essential role in the maturation and differentiation of T cells, which are critical for adaptive immunity. Thymosin alpha 1 has been studied for its potential in treating various immune-related conditions, including viral infections, autoimmune disorders, and cancer.

Glutathione peptides, which are made up of three amino acids, have strong antioxidant capabilities. By neutralizing damaging free radicals, they may help protect the body from oxidative stress.

Copper Peptides (GHK-Cu)

Copper peptides, like GHK-Cu, may be utilized to regenerate skin and fight aging. They have the potential to help in the stimulation of collagen formation, the reduction of inflammation, and the promotion of wound healing.

These peptides are generally used topically in skincare products at concentrations ranging from 0.5% to 5%. They can be coupled with other peptides like Matrixyl to increase the potential of boosting skin regeneration.

Melanocortin receptor peptides, such as Melanotan II, may be utilized for a variety of purposes, including promoting skin tanning, suppressing hunger, and improving sexual performance.

They function by activating certain melanocortin receptors in the body, which results in a variety of physiological effects. Although there is a lack of scientific evidence, this family of peptides is believed to have a positive effect on muscle growth and recovery.

The dosage of melanocortin receptor peptides varies greatly based on the application and individual requirements. In most cases, a medical professional will need to be consulted to determine the ideal dosing. 

Matrixyl, also known as palmitoyl pentapeptide-4, is a synthetic peptide that could potentially be used to promote skin regeneration and anti-aging.

It has the potential to promote the formation of collagen, elastin, and other extracellular matrix proteins, which help in the maintenance of skin structure and suppleness.

Matrixyl has shown evidence to boost skin texture and firmness, as well as lessen the appearance of fine lines and wrinkles. It is frequently coupled with other peptides, such as copper peptides (GHK-Cu), to increase its effects. Topically, Matrixyl is generally used in skin care products in concentrations ranging from 0.5% to 5%, depending on the formulation and desired results.

Ghrelin agonists are synthetic peptides that imitate the effects of the natural hormone ghrelin, which regulates hunger and energy balance. Ghrelin agonists have been examined for their ability to promote weight gain and muscle growth, particularly in people suffering from chronic diseases such as cancer or AIDS, which cause severe weight loss and muscle atrophy.

Ghrelin agonists function by binding to the ghrelin receptor, which is found in many tissues such as the brain, pituitary gland, and gastrointestinal tract.

This binding might help enhance growth hormone release, increase appetite, and promote fat storage, resulting in weight gain and muscle building. 

When it comes to dosing, the amount required will vary greatly due to its range of applications. Before beginning any treatment with ghrelin agonists, it is critical to check with a healthcare expert because they may have potential side effects and interactions with other medications.

injured knee

Acetyl Hexapeptide-8, also known as Argireline, is a synthetic peptide noted for its muscle-relaxing properties. It is often associated with reducing the visibility of fine lines and wrinkles, sometimes compared to “topical Botox.”

The action of these peptides involves the inhibition of neurotransmitter release, which can lead to muscle spasms. This process may lead to a temporary relaxation of facial muscles, potentially smoothing wrinkles and fine lines, particularly on the forehead and around the eyes. Argireline is typically included in topical skincare treatments at concentrations of about 10%.

While Argireline may provide some immediate improvements in the appearance of wrinkles, the effects are only temporary, and regular use might be required to maintain the results.

Palmitoyl Pentapeptide-3, also known as Matrixyl, is a synthetic peptide featured in cosmetic products for its anti-aging properties. It is associated with stimulating the production of collagen, elastin, and other extracellular matrix proteins, contributing to the maintenance of skin structure and elasticity. These peptides are linked to reducing the visibility of fine lines and wrinkles, improving skin texture, and increasing skin firmness through the promotion of collagen production.

Palmitoyl Pentapeptide-3 is commonly used topically in skincare products, often in combination with other peptides like copper (GHK-Cu) to amplify its effects.

The level of these peptides in skincare products can differ, based on the formulation and the intended outcomes.

IGF-1 (insulin-like growth factor 1) is a hormone that has a similar structure to insulin. It is essential for childhood growth and development and continues to have anabolic effects in adulthood.

IGF-1 is involved with stimulating cell growth, differentiation, and survival and regulates glucose and lipid metabolism. IGF-1 may be used therapeutically because it has the potential to promote muscle growth, improve bone density, and aid in tissue healing. While substantial research is already done on IGF-1, more research is needed to fully understand the full potential of this hormone.

The use of IGF-1 as a treatment is still being researched, and it is critical to seek the advice of a healthcare professional before considering its use.

Growth Hormone-Releasing Peptides (GHRP)

Growth hormone-releasing peptides (GHRPs) are synthetic peptides that trigger the pituitary gland’s growth hormone production (GH)

They have been the potential to boost muscular development, increase hunger, and aid the body’s overall growth and healing processes. GHRPs such as GHRP-2, GHRP-6, and ipamorelin are examples of GHRPs.

The dosage of GHRPs varies according to the peptide utilized and the individual’s demands. It is crucial to highlight that the usage of GHRPs is currently under investigation, and they should only be used under the supervision of a healthcare expert.

hand with glove holding an injection piercing a vial with fluid

Adipotide

Adipotide is a peptide that showed some promise to help with obesity in a study with monkeys. It works by decreasing the blood flow to fat cells, resulting in a reduction in body fat. However the only human study was discontinued in 2019.

Keratin Peptides

Keratin is often used to promote strong hair. Frequently found in hair care products and are administered topically. Keratin peptides may help increase hair strength, resilience, and overall look by improving the structural integrity of hair strands.

Biotinoyl Tripeptide-1

Similar to Keratin peptides, Biotinyl tripeptide-1 is commonly found in hair care products that help stimulate hair growth and fortify hair follicles. It works by stimulating the hair follicle cells, resulting in greater hair growth and better hair quality. Biotinoyl tripeptide-1 is commonly used topically in numerous hair care products.

DPP-4 Inhibitors

DPP-4 inhibitors are peptides used to regulate blood sugar levels in type 2 diabetic patients. They function by inhibiting the activity of the DPP-4 enzyme, which helps extend the activity of incretin hormones, which are important for reducing blood sugar levels. The dosage of DPP-4 inhibitors depends on the application and an individual’s specific needs.

Ipamorelin

Ipamorelin is a growth hormone-releasing peptide (GHRP). GHRPs release growth hormone slowly and steadily in a way that mimics the release timing of natural growth hormone (GH) and growth hormone-releasing hormone (GHRH). Ipamorelin has two main mechanisms of action: increasing your body’s levels of natural GHRH and restraining the somatostatin hormone that hinders your body from producing growth hormone. Ipamorelin works  quickly, and has about a two-hour half-life.

Glucagon-like peptide-1 (GLP-1) analogs are a family of drugs used to help individuals with type 2 diabetes regulate their blood sugar levels. They are structurally identical to the natural incretin hormone GLP-1, which regulates glucose metabolism. 

GLP-1 analogs function by boosting pancreatic insulin production, decreasing glucagon release, and slowing gastric emptying, resulting in better blood sugar control. Exenatide (Byetta), liraglutide (Victoza), and semaglutide are examples of well-known GLP-1 analogs (Ozempic). 

These drugs are often given as injections and are used in conjunction with other diabetic therapies, such as oral medications and lifestyle changes.

Melanotan II is a synthetic peptide that functions similarly to the natural hormone alpha-melanocyte-stimulating hormone (-MSH). It works by increasing melanin production, the pigment responsible for skin color, resulting in a darker skin tone. 

This peptide has been studied for its possible use as a tanning agent as well as a treatment for some skin conditions, such as erythropoietic protoporphyria. Melanotan II dosage varies; however, it is usually given as an injection.

The synthetic peptide TB-500, commonly known as thymosin beta-4, has been researched for its tissue repair and regeneration characteristics.

It has been demonstrated that it promotes cell migration, angiogenesis, and collagen deposition, all of which are required for wound healing and tissue repair. 

TB-500 is thought to work by influencing the expression of specific genes involved in tissue repair processes and interacting with the extracellular matrix, which provides structural support to cells and tissues. The weekly dose of TB-500 can range from 2.0 to 2.5 mg, with some requiring multiple doses each week for severe injury or surgery recovery.

The heart secretes B-type natriuretic peptide (BNP) in response to stretching or increasing pressure. It works as a vasodilator, relaxing blood vessels and lowering blood pressure. BNP also induces diuresis and natriuresis, which aid in reducing fluid retention in the body.

BNP levels in the blood can be elevated in the presence of heart failure, making it a useful diagnostic tool for clinicians. High doses of BNP or its synthetic counterpart, nesiritide, may be used to treat acute heart failure. 

This treatment seeks to relieve symptoms by increasing vasodilation and decreasing fluid excess in the body. The use of BNP as a treatment is normally reserved for severe instances and should only be delivered under the supervision of a healthcare practitioner.

Vasoactive intestinal peptide (VIP) is well-known for its vasodilatory effects, which aid in the dilation of blood vessels and the improvement of blood flow. VIP may be used to treat some respiratory, gastrointestinal, and neurological diseases, though its application is currently being studied and is not extensively employed in clinical practice.

PT-141

PT-141 (also known as bremelanotide) is a synthetic peptide typically used to help enhance sexual activity in men and women.1 It is a melanocyte-stimulating hormone (MSH) that works by activating neurons in the brain’s hypothalamus region to increase sexual desire.

This peptide helps increase libido in both men and women and may help cause erections in men.2 In a study of premenopausal women with hypoactive sexual desire disorder (HSDD), PT-141 helped increase sexual desire and reduced distress.3

Angiotensin-converting enzyme inhibitors, rather than peptides, are a type of drug often used to treat high blood pressure and other cardiovascular diseases. They act by inhibiting the enzyme that converts angiotensin I to angiotensin II, a strong vasoconstrictor. This lowers blood pressure and lowers the risk of heart problems.

Thymosin 4 is a peptide that is used for tissue repair and regeneration. It has been demonstrated that it promotes cell migration, angiogenesis, and collagen deposition, all of which are required for wound healing and tissue repair. Thymosin 4 dosage varies according to the individual’s needs and unique goals.

Sermorelin

Sermorelin is a synthetic form of GHRH that might be able to correct low levels of HGH in children and adults, but it is most beneficial for children. It may also help treat certain types of recurrent brain tumors.4

HGH is most important for children and adolescents, but it is necessary to keep your organs and tissues healthy throughout your life. Having HGH levels that are too high or too low can cause health problems in people of all ages.

The potential benefits of sermorelin injections include:

  • General well-being
  • Insulin sensitivity
  • Lean body mass
  • Libido

Because sermorelin is a secretagogue of HGH, it might increase your HGH levels by stimulating your pituitary gland to create HGH naturally. This would help avoid the risks and side effects associated with having natural HGH injected.

Good candidates for treatment with Sermorelin are people with low HGH levels. Healthy adults can also take Sermorelin because it may help with anti-aging and bodybuilding, but there is limited scientific evidence to support using Sermorelin for these purposes.

You should not take Sermorelin if you are allergic to Sermorelin, have untreated hypothyroidism, or are pregnant, breastfeeding, or may become pregnant.

Conclusion

The study of peptides, their numerous uses, and the possible combinations they provide highlights the incredible variety and promise these chemicals represent in the domains of healthcare, beauty, and beyond. We’ve seen peptides’ capacity to address a wide range of health and cosmetic issues as we’ve dug into the many functions they play, from skincare to therapeutic therapies.

Furthermore, the notion of mixing peptides has opened up fascinating new avenues for bespoke solutions to unique demands and issues. The future of peptides is extremely bright, with unlimited prospects for boosting our well-being and unlocking new vistas in the fields of science and self-care thanks to continuing research and innovation.

Revitalize With Peptide Therapy

Peptides are short chains of amino acids that serve as building blocks for proteins and play crucial roles in many biological functions. Combat age-related decline of peptides in your body with our scientifically formulated peptides, which offer a range of health benefits:

SERMORELIN - Boost lean muscle & reduce fat.

GHK-CU - Promote skin rejuvenation & firmness.

PT-141 - Intensify sexual desire & function.

Order today and receive your peptides at home, where you can self-administer your treatments with ease.

Peptide Shots - Frequently Asked Questions

What is included in our peptides injections?

There are many different peptide injections that we offer as part of a peptide therapy including Sermorelin, GHK-CU and PT-141.

What is SERMORELIN?

Sermorelin is a synthetic form of GHRH (growth hormone-releasing hormone) which controls the hGH (human growth hormone) and it’s recommended to people who have low levels of hGH. 

How do peptides improve your sleep?

Serotonin is a neurotransmitter present in the brain that releases chemicals as messages to your brain and body that it is time to go to sleep. Some peptides can interact with serotonin. Serotonin regulation issues can definitely interfere with a person's ability to have a good night's sleep.

Sermorelin is recognized for their potency as peptides that may potentially enhance sleep.

How do peptides improve immune health?

The immune response can be either blocked or stimulated to produce tolerance using peptides and peptidomimetics as immunomodulating agents.

Read more: Peptide Shots FAQ

References

[1] Molinoff PB. - PT-141: a melanocortin agonist for the treatment of sexual dysfunction;

[2] King SH. - Melanocortin Receptors, Melanotropic Peptides and Penile Erection;

[3] Clayton AH. - Bremelanotide for Female Sexual Dysfunctions in Premenopausal Women: A Randomized, Placebo-Controlled Dose-Finding Trial;

[4] Chang Y. - A potentially effective drug for patients with recurrent glioma: sermorelin;