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With things moving at such a fast pace, there has been an increased need for convenient health solutions. Thanks to advances in medical technology, the quantity of health solutions has exploded in recent years. Of the treatments currently available, many people are taking the time to research the effectiveness of peptides and their ability to improve different aspects of their health.

Peptides are short chains of amino acids, and due to their capacity to interact with and control a variety of biological processes, they have the potential to be used in a wide variety of therapeutic applications.

Peptide Therapy

From combating aging to boosting muscle development and recovery and more, peptide treatments can help you achieve a wide range of health goals. Our peptide treatments are delivered to your doorstep and self-administered in the comfort of your home.

GHK-Cu | PT-141 | Sermorelin

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In recent years, peptides have had a meteoric rise in popularity, particularly in the fields of medicine, the beauty industry, and the fitness industry. To help you understand the benefits of various peptides, we have compiled this comprehensive guide to some of the most promising options.

LL-37 is an antimicrobial peptide from the cathelicidin family.

It is predominantly produced by immune and epithelial cells in response to infection or inflammation. LL-37 has been shown to have potent antibacterial and anti-inflammatory properties, supporting the body in combating a variety of illnesses such as bacteria, viruses, and fungi. 

This peptide has been demonstrated to improve wound healing by increasing cell migration, angiogenesis, and the generation of growth factors, in addition to its antimicrobial activity. LL-37 dosage varies according to the condition being treated, and it can be coupled with other peptides.

Beta-defensins are an antimicrobial peptide family that plays critical roles in the immune system.

They are largely produced by epithelial cells and aid in the body’s defense against a variety of pathogens, such as bacteria, viruses, and fungi. Beta-defensins act by compromising pathogen membrane integrity, resulting in their destruction.

They also possess immune control properties, helping to regulate the immune system to respond properly and reduce inflammation. The dosage of beta-defensins required to achieve this will vary depending on the condition being treated. Beta-defensins can be used in conjunction with other peptides, such as LL-37.

Thymosin alpha 1 is a peptide with immune system-boosting properties. 

It plays an essential role in the maturation and differentiation of T cells, which are critical for adaptive immunity. Thymosin alpha 1 has been studied for its potential in treating various immune-related conditions, including viral infections, autoimmune disorders, and cancer.

It has also been shown to enhance vaccine efficacy by improving the immune response to antigens. The dosage of thymosin alpha 1 typically ranges from 1 to 2 mg per week, depending on the individual’s needs and the condition being treated. It can be combined with other peptides, such as LL-37 and beta-defensins, for synergistic effects.

Glutathione peptides, which are made up of three amino acids, have strong antioxidant capabilities. By neutralizing damaging free radicals, they help protect the body from oxidative stress.

Just as with other peptides, dosing for glutathione peptides will vary depending on an individual’s situation. However, the common range is from 100-600 mg per day. Depending on the desired effect, these peptides can be administered orally, topically, or intravenously.

Copper Peptides (GHK-Cu)

Copper peptides, like GHK-Cu, are utilized to regenerate skin and fight aging. They aid in the stimulation of collagen formation, the reduction of inflammation, and the promotion of wound healing.

These peptides are generally used topically in skincare products at concentrations ranging from 0.5% to 5%. They can be coupled with other peptides like Matrixyl to boost skin regeneration.

Melanocortin receptor peptides, such as Melanotan II, are utilized for a variety of purposes, including promoting skin tanning, suppressing hunger, and improving sexual performance.

They function by activating certain melanocortin receptors in the body, which results in a variety of physiological effects. Although there is a lack of scientific evidence, this family of peptides is believed to have a positive effect on muscle growth and recovery.

The dosage of melanocortin receptor peptides varies greatly based on the application and individual requirements. In most cases, a medical professional will need to be consulted to determine the ideal dosing. 

Matrixyl, also known as palmitoyl pentapeptide-4, is a synthetic peptide used to promote skin regeneration and anti-aging.

It promotes the formation of collagen, elastin, and other extracellular matrix proteins, which help in the maintenance of skin structure and suppleness.

Matrixyl has been proven to boost skin texture and firmness, as well as lessen the appearance of fine lines and wrinkles. It is frequently coupled with other peptides, such as copper peptides (GHK-Cu), to increase its effects. Topically, Matrixyl is generally used in skin care products in concentrations ranging from 0.5% to 5%, depending on the formulation and desired results.

Ghrelin agonists are synthetic peptides that imitate the effects of the natural hormone ghrelin, which regulates hunger and energy balance. Ghrelin agonists have been examined for their ability to promote weight gain and muscle growth, particularly in people suffering from chronic diseases such as cancer or AIDS, which cause severe weight loss and muscle atrophy.

Ghrelin agonists function by binding to the ghrelin receptor, which is found in many tissues such as the brain, pituitary gland, and gastrointestinal tract.

This binding can enhance growth hormone release, increase appetite, and promote fat storage, resulting in weight gain and muscle building. 

When it comes to dosing, the amount required will vary greatly due to its range of applications. Before beginning any treatment with ghrelin agonists, it is critical to check with a healthcare expert because they may have potential side effects and interactions with other medications.

BPC-157

BPC-157, also known as body protection compound 157, is a synthetic peptide that has been shown to have various healing and regenerative properties. 

It has been studied for its ability to aid in tissue repair, reduce inflammation, and accelerate wound healing.  This synthetic peptide is thought to work by interacting with several cellular pathways involved in tissue repair and regeneration, including regulating growth factors and modulating inflammatory responses.

The dosage of BPC-157 typically ranges from 100 mcg to 500 mcg per day, depending on individual needs and goals.

injured knee

Acetyl Hexapeptide-8, often known as Argireline, is a synthetic peptide with muscle-relaxing characteristics. Because of its ability to minimize the appearance of fine lines and wrinkles, it is frequently referred to as “topical Botox.”

These peptides work by preventing the release of neurotransmitters that cause muscular spasms, resulting in a temporary relaxation of the facial muscles. This relaxation can help to smooth out wrinkles and fine lines, especially on the forehead and around the eyes. Argireline is commonly found in topical skincare treatments in quantities of roughly 10%. 

While Argireline may provide some immediate improvements in the appearance of wrinkles, the effects are only temporary, and regular use is required to maintain the results.

Palmitoyl Pentapeptide-3, or Matrixyl, is a synthetic peptide with anti-aging characteristics utilized in cosmetic products. It promotes the formation of collagen, elastin, and other extracellular matrix proteins, which aid in the maintenance of skin structure and suppleness. These peptides have been found to minimize the appearance of fine lines and wrinkles, enhance skin texture, and boost skin firmness by enhancing collagen formation.

Palmitoyl Pentapeptide-3 is typically applied topically in skincare products, often combined with other peptides like copper (GHK-Cu) to enhance its effects. 

The concentration of these peptides in skincare products can vary, depending on the formulation and desired results.

IGF-1 (insulin-like growth factor 1) is a hormone that has a similar structure to insulin. It is essential for childhood growth and development and continues to have anabolic effects in adulthood.

IGF-1 stimulates cell growth, differentiation, and survival and regulates glucose and lipid metabolism. IGF-1 may be used therapeutically to promote muscle growth, improve bone density, and aid in tissue healing. While substantial research is already done on IGF-1, more research is needed to fully understand the potential of this hormone.

The use of IGF-1 as a treatment is still being researched, and it is critical to seek the advice of a healthcare professional before considering its use.

Growth Hormone-Releasing Peptides (GHRP)

Growth hormone-releasing peptides (GHRPs) are synthetic peptides that trigger the pituitary gland’s growth hormone production (GH)

They have been demonstrated to boost muscular development, increase hunger, and aid the body’s overall growth and healing processes. GHRPs such as GHRP-2, GHRP-6, and ipamorelin are examples of GHRPs.

The dosage of GHRPs varies according to the peptide utilized and the individual’s demands. It is crucial to highlight that the usage of GHRPs is currently under investigation, and they should only be used under the supervision of a healthcare expert.

hand with glove holding an injection piercing a vial with fluid

Adipotide

Adipotide is a peptide that is commonly used in concert with diet and exercise to decrease body fat. It works by decreasing the blood flow to fat cells, resulting in a reduction in body fat. Adipotide peptide dosage varies depending on the unique use case and individual demands.

Keratin Peptides

Keratin peptides are often used to promote strong hair. They are frequently found in hair care products and are administered topically. Keratin peptides can help increase hair strength, resilience, and overall look by improving the structural integrity of hair strands.

Biotinoyl Tripeptide-1

Similar to Keratin peptides, Biotinyl tripeptide-1 is commonly found in hair care products that help stimulate hair growth and fortify hair follicles. It works by stimulating the hair follicle cells, resulting in greater hair growth and better hair quality. Biotinoyl tripeptide-1 is commonly used topically in numerous hair care products.

DPP-4 Inhibitors

DPP-4 inhibitors are peptides used to regulate blood sugar levels in type 2 diabetic patients. They function by inhibiting the activity of the DPP-4 enzyme, which helps extend the activity of incretin hormones, which are important for reducing blood sugar levels. The dosage of DPP-4 inhibitors depends on the application and an individual’s specific needs.

CJC-1295/Ipamorelin

CJC-1295 and Ipamorelin are two peptides that are often used together. Each one is potent when used independently but is most effective when combined.

  • CJC-1295 is a synthetic analog of GHRH that stimulates the anterior pituitary gland to release human growth hormone (HGH).
  • Ipamorelin is a growth hormone-releasing peptide (GHRP). GHRPs release growth hormone slowly and steadily in a way that mimics the release timing of natural growth hormone (GH) and growth hormone-releasing hormone (GHRH). Ipamorelin has two main mechanisms of action: increasing your body’s levels of natural GHRH and restraining the somatostatin hormone that hinders your body from producing growth hormone.

It takes between one and four hours for CJC-1295 to reach peak serum levels in the blood. Ipamorelin works more quickly than CJC-1295, but it is also eliminated from the body in a shorter period of time than CJC-1295 because Ipamorelin has about a two-hour half-life.

These peptides work well together because ipamorelin kicks in quickly, and CJC-1295 ensures lasting effects.

Glucagon-like peptide-1 (GLP-1) analogs are a family of drugs used to help individuals with type 2 diabetes regulate their blood sugar levels. They are structurally identical to the natural incretin hormone GLP-1, which regulates glucose metabolism. 

GLP-1 analogs function by boosting pancreatic insulin production, decreasing glucagon release, and slowing gastric emptying, resulting in better blood sugar control. Exenatide (Byetta), liraglutide (Victoza), and semaglutide are examples of well-known GLP-1 analogs (Ozempic). 

These drugs are often given as injections and are used in conjunction with other diabetic therapies, such as oral medications and lifestyle changes.

Melanotan II is a synthetic peptide that functions similarly to the natural hormone alpha-melanocyte-stimulating hormone (-MSH). It works by increasing melanin production, the pigment responsible for skin color, resulting in a darker skin tone. 

This peptide has been studied for its possible use as a tanning agent as well as a treatment for some skin conditions, such as erythropoietic protoporphyria. Melanotan II dosage varies; however, it is usually given as an injection.

The synthetic peptide TB-500, commonly known as thymosin beta-4, has been researched for its tissue repair and regeneration characteristics.

It has been demonstrated that it promotes cell migration, angiogenesis, and collagen deposition, all of which are required for wound healing and tissue repair. 

TB-500 is thought to work by influencing the expression of specific genes involved in tissue repair processes and interacting with the extracellular matrix, which provides structural support to cells and tissues. The weekly dose of TB-500 can range from 2.0 to 2.5 mg, with some requiring multiple doses each week for severe injury or surgery recovery.

DSIP

DSIP (delta sleep-inducing peptide) is a neuromodulator and nonapeptide that has been studied for over 40 years. It is naturally present in the brain and easily moves through the blood-brain barrier (BBB). DSIP has many potential physiological benefits and can be useful in treating low testosterone, pain, poor sleep, and stress-related symptoms.

There are five sleep stages and two categories of sleep: rapid eye movement (REM) and non-REM (NREM). Many important physiological processes happen during each sleep stage, and anabolic hormones are produced. Many sleep aids work by affecting the time or duration of sleep cycles, which may alter these physiological processes and hormone production, but DSIP works by helping regulate your circadian rhythm, which may help you fall asleep and provide you with more restful sleep. It does not shorten or lengthen the time your body has during each sleep stage.

In humans, DSIP also stimulates the secretion of adrenocorticotropic hormone (ACTH), growth hormone (GH), and luteinizing hormone (LH). Like Ipamorelin, DSIP decreases the production of somatosin and a stress hormone called cortisol. Its stimulation of LH makes it useful in helping treat low testosterone, and its reduction of the production of stress hormones makes DSIP useful in treating stress issues.

The heart secretes B-type natriuretic peptide (BNP) in response to stretching or increasing pressure. It works as a vasodilator, relaxing blood vessels and lowering blood pressure. BNP also induces diuresis and natriuresis, which aid in reducing fluid retention in the body.

BNP levels in the blood can be elevated in the presence of heart failure, making it a useful diagnostic tool for clinicians. High doses of BNP or its synthetic counterpart, nesiritide, may be used to treat acute heart failure. 

This treatment seeks to relieve symptoms by increasing vasodilation and decreasing fluid excess in the body. The use of BNP as a treatment is normally reserved for severe instances and should only be delivered under the supervision of a healthcare practitioner.

Vasoactive intestinal peptide (VIP) is well-known for its vasodilatory effects, which aid in the dilation of blood vessels and the improvement of blood flow. VIP may be used to treat some respiratory, gastrointestinal, and neurological diseases, though its application is currently being studied and is not extensively employed in clinical practice.

PT-141

PT-141 (also known as bremelanotide) is a synthetic peptide typically used to help enhance sexual activity in men and women.1 It is a melanocyte-stimulating hormone (MSH) that works by activating neurons in the brain’s hypothalamus region to increase sexual desire.

This peptide helps increase libido in both men and women and helps cause erections in men.2 In a study of premenopausal women with hypoactive sexual desire disorder (HSDD), PT-141 helped increase sexual desire and reduced distress.3

Angiotensin-converting enzyme inhibitors, rather than peptides, are a type of drug often used to treat high blood pressure and other cardiovascular diseases. They act by inhibiting the enzyme that converts angiotensin I to angiotensin II, a strong vasoconstrictor. This lowers blood pressure and lowers the risk of heart problems.

Thymosin 4 is a peptide that is used for tissue repair and regeneration. It has been demonstrated that it promotes cell migration, angiogenesis, and collagen deposition, all of which are required for wound healing and tissue repair. Thymosin 4 dosage varies according to the individual’s needs and unique goals.

Sermorelin

Sermorelin is a synthetic form of GHRH that can be used to correct low levels of HGH in children and adults, but it is most beneficial for children. It may also help treat certain types of recurrent brain tumors.4

HGH is most important for children and adolescents, but it is necessary to keep your organs and tissues healthy throughout your life. Having HGH levels that are too high or too low can cause health problems in people of all ages.

The potential benefits of sermorelin injections include:

  • General well-being
  • Insulin sensitivity
  • Lean body mass
  • Libido

Because sermorelin is a secretagogue of HGH, it increases your HGH levels by stimulating your pituitary gland to create HGH naturally. This helps avoid the risks and side effects associated with having natural HGH injected..

Good candidates for treatment with Sermorelin are people with low HGH levels. Healthy adults can also take Sermorelin to help with anti-aging and bodybuilding, but there is limited scientific evidence to support using Sermorelin for these purposes.

You should not take Sermorelin if you are allergic to Sermorelin, have untreated hypothyroidism, or are pregnant, breastfeeding, or may become pregnant.

Conclusion

The study of peptides, their numerous uses, and the possible combinations they provide highlights the incredible variety and promise these chemicals represent in the domains of healthcare, beauty, and beyond. We’ve seen peptides’ capacity to address a wide range of health and cosmetic issues as we’ve dug into the many functions they play, from skincare to therapeutic therapies.

Furthermore, the notion of mixing peptides has opened up fascinating new avenues for bespoke solutions to unique demands and issues. The future of peptides is extremely bright, with unlimited prospects for boosting our well-being and unlocking new vistas in the fields of science and self-care thanks to continuing research and innovation.

Revitalize With Peptide Therapy

Peptides are short chains of amino acids that serve as building blocks for proteins and play crucial roles in many biological functions. Combat age-related decline of peptides in your body with our scientifically formulated peptides, which offer a range of health benefits:

SERMORELIN - Boost lean muscle & reduce fat.

GHK-CU - Promote skin rejuvenation & firmness.

PT-141 - Intensify sexual desire & function.

Order today and receive your peptides at home, where you can self-administer your treatments with ease.

Peptide Shots - Frequently Asked Questions

What is included in our peptides injections?

There are many different peptide injections that we offer as part of a peptide therapy including Sermorelin, GHK-CU and PT-141.

What is SERMORELIN?

Sermorelin is a synthetic form of GHRH (growth hormone-releasing hormone) which controls the hGH (human growth hormone) and it’s recommended to people who have low levels of hGH. 

How do peptides improve your sleep?

Serotonin is a neurotransmitter present in the brain that releases chemicals as messages to your brain and body that it is time to go to sleep. Some peptides can interact with serotonin. Serotonin regulation issues can definitely interfere with a person's ability to have a good night's sleep.

Sermorelin is recognized for their potency as peptides that enhance sleep.

How do peptides improve immune health?

The immune response can be either blocked or stimulated to produce tolerance using peptides and peptidomimetics as immunomodulating agents.

Read more: Peptide Shots FAQ

References

[1] Molinoff PB. - PT-141: a melanocortin agonist for the treatment of sexual dysfunction;

[2] King SH. - Melanocortin Receptors, Melanotropic Peptides and Penile Erection;

[3] Clayton AH. - Bremelanotide for Female Sexual Dysfunctions in Premenopausal Women: A Randomized, Placebo-Controlled Dose-Finding Trial;

[4] Chang Y. - A potentially effective drug for patients with recurrent glioma: sermorelin;