Ketamine Nasal Spray is an innovative treatment for individuals struggling with treatment-resistant depression (TRD)—a form of depression that does not respond to standard antidepressants. Unlike traditional medications that can take weeks to work, ketamine (including racemic ketamine and esketamine) targets NMDA receptors in the brain, improving synaptic connections and enhancing mood-regulating pathways.
Esketamine, the FDA-approved form of ketamine nasal spray, has shown clinical benefits as early as 24 hours, while racemic ketamine – used off-label -has also demonstrated significant reductions in depressive symptoms.
Returning customer? You can login here or continue as a guest checkout
Close
Billing Address
Frequently asked questions
What is ketamine nasal spray used for?
Ketamine nasal spray is primarily used for treatment-resistant depression, especially in individuals who have not found relief with standard antidepressants. It may also reduce suicidal thoughts and improve outcomes when used alongside therapy.
How quickly does ketamine nasal spray work?
Unlike traditional antidepressants that may take weeks, ketamine nasal spray can show results within 24 hours. Some patients experience improved mood, energy, and outlook after their first dose.
Is ketamine nasal spray safe?
When prescribed and monitored by a medical provider, ketamine nasal spray is generally well-tolerated. Side effects may include dizziness, nausea, or dissociation, but these are typically temporary. ConciergeMD ensures structured safety monitoring for every patient.
What’s the difference between esketamine and racemic ketamine?
Esketamine is the FDA-approved nasal spray for treatment-resistant depression, administered under strict safety protocols.
Racemic ketamine is used off-label and has also shown rapid antidepressant effects. Both forms act on NMDA receptors to boost brain connectivity.
How do I know if I’m a candidate for ketamine nasal spray?
You may be a candidate if you have major depressive disorder that has not responded to at least two antidepressant medications. ConciergeMD’s medical evaluation will determine eligibility and the best treatment approach.
Processing your booking, please wait...Please don't close the browser window until you see the confirmation page (can take longer for larger bookings).
Do not refresh this page. If loading takes a few minutes, call (888) 310-2630 to confirm your booking.
Do not refresh this page. If loading takes a few minutes, call (888) 310-2630 to confirm your booking.
Processing your booking, please wait...
