hand holding a syringe with red fluid inside

Sermorelin For Athletes: Exploring The Benefits And Legalities In Sports

Growth hormone (GH), which is essential for fat loss, cardiovascular health, and muscular growth, is stimulated by the pituitary gland by sermorelin, a synthetic form of growth hormone-releasing hormone (GHRH).(1,2,3) Studies reveal that when compared to growth hormone therapies, sermorelin can improve muscular endurance and lean body mass with fewer adverse effects. Nonetheless, it is prohibited by organizations that oversee sports, such as the U.S. Anti-Doping Agency and WADA. Its long-term safety has to be investigated further, and it should only be used under medical supervision.


Boost your vitality and performance with Sermorelin. Experience benefits like enhanced muscle growth, improved energy, and faster recovery in the comfort of home.

As an athlete, trying to find the best ways to achieve the best physique can be frustrating. The market is flooded with products, many of which are unregulated and unproven. Further complicating matters are the regulations surrounding treatments and supplements designed to help reach physical goals.

Sermorelin, a growth hormone-releasing hormone (GHRH) analog, has gained attention in the athletic world as a performance-enhancing treatment. What are the benefits of supplementing sermorelin? How do sports organizations view this GHRH analog? Keep reading for the information you need to determine if sermorelin is the right choice for you.

What is Sermorelin?

Sermorelin is a synthetic version of growth hormone-releasing hormone (GHRH) which stimulates the pituitary gland located at the base of the brain.

Among other hormones, the pituitary gland produces growth hormone (GH), which serves a pivotal function in many body processes such as muscle loss, weight management, and cardiovascular health. Sermorelin, like GHRH, signals the pituitary gland to produce GH.

GH is instrumental in numerous physiological processes, including the development and maintenance of muscle tissue.

hand holding a syringe with red fluid inside

It aids in muscle growth (hypertrophy), promotes the repair and recovery of muscle fibers after exercise, and impacts overall physical performance. Increasing GH levels has been studied as a means of improving athletic performance and fighting the effects of aging.

Benefits of Sermorelin for Athletes

A number of studies have demonstrated the positive effects of increased GH for muscle build and combating the effects of aging on physical ability.

A 2013 study resulted in a significant increase in leg strength in men aged 50-70 years old after receiving GH therapy for six months.4 In a review of 31 studies, lean muscle mass gains and body fat losses averaged between 4-5 pounds. However, significant side effects were noted in these studies, including carpal tunnel syndrome, fluid retention, and breast enlargement.

Sermorelin studies have noted far fewer and less severe side effects than GH treatments, which is attributed to sermorelin working similarly to naturally occuring GHRH.5

Sermorelin consistently demonstrated longer-lasting results than GH treatments, increasing GH production without pushing GH levels outside their natural peak ranges in participants. Significant improvements in muscle endurance were also observed. While there were not significant differences in body weight, lean body mass increased significantly. Unlike GH treatments, sermorelin appears to be well-suited for longer-term use, though more research is needed.

Legal and Ethical Considerations in Sports

Although sermorelin is being studied as a safer alternative to other performance-enhancing drugs, it is still banned by sports regulatory entities including the World Anti Doping Agency (WADA) and the U.S. Anti-Doping Agency. If you are involved in athletic leagues that test for performance-enhancing drugs, you should consult an experienced attorney or an experienced coach before beginning sermorelin treatment.

Safety and Side Effects

More research is needed to determine the long-term side effects of sermorelin. Most of the known side effects of sermorelin are mild, such as:

  • Pain, redness, or itchiness at the injection site
  • Restlessness
  • Headache
  • Dizziness
  • Fatigue
  • Feeling flush

People with thyroid conditions should be cautious when considering sermorelin treatments. Drug interactions can vary on a case-by-case basis. You should only seek treatments from experienced, licensed doctors who can conduct a full evaluation to ensure sermorelin is a safe, effective treatment for you.

Comparisons with Other Performance Enhancements

As previously noted, sermorelin mimics naturally-occuring GHRH, increasing GH levels without causing extreme or erratic fluctuations. Increasing GH in the body without causing sharp increases far beyond natural peaks lessens the risk and severity of potential side effects. Despite this distinction, sermorelin remains banned by most sports organizations, similarly to other performance-enhancing treatments.

Final Thoughts

Sermorelin offers many potential benefits for athletes, particularly in areas of muscle recovery and overall performance. However, despite demonstrating fewer side effects than most other performance enhancers, it remains banned by most regulatory authorities in the athletic world. Any athlete interested in sermorelin should consult a healthcare professional as well as an experienced coach or attorney to ensure it is the safest and best treatment to achieve athletic goals.


Sermorelin is a peptide that helps stimulate the production and release of growth hormone (GH), which can support improved physical performance, vitality, and body composition. Potential benefits include increased muscle mass, fat loss, faster recovery, stronger immune function, improved bone density, and heightened energy. Get treatments delivered to your home and experience the power of Sermorelin.

Peptide Shots - Frequently Asked Questions

What is included in our peptide injections?

There are many different peptide injections that we offer as part of a peptide therapy including Sermorelin and PT-141.


Sermorelin is a synthetic form of GHRH (growth hormone-releasing hormone) which controls the hGH (human growth hormone) and it’s recommended to people who have low levels of hGH. 

How do peptides improve your sleep?

Serotonin is a neurotransmitter present in the brain that releases chemicals as messages to your brain and body that it is time to go to sleep. Some peptides can interact with serotonin. Serotonin regulation issues can definitely interfere with a person's ability to have a good night's sleep.

Sermorelin is recognized for their potency as peptides that may potentially enhance sleep.

How do peptides improve immune health?

The immune response can be either blocked or stimulated to produce tolerance using peptides and peptidomimetics as immunomodulating agents.

Read more: Peptide Shots FAQ


[1] Kim KR, Nam SY, Song YD, Lim SK, Lee HC, Huh KB. Low-dose growth hormone treatment with diet restriction accelerates body fat loss, exerts anabolic effect and improves growth hormone secretory dysfunction in obese adults. Horm Res. 1999;51(2):78-84. doi: 10.1159/000023319. PMID: 10352397.;

[2] Caicedo D, Díaz O, Devesa P, Devesa J. Growth Hormone (GH) and Cardiovascular System. Int J Mol Sci. 2018 Jan 18;19(1):290. doi: 10.3390/ijms19010290. PMID: 29346331; PMCID: PMC5796235.;

[3] Tavares AB, Micmacher E, Biesek S, Assumpção R, Redorat R, Veloso U, Vaisman M, Farinatti PT, Conceição F. Effects of Growth Hormone Administration on Muscle Strength in Men over 50 Years Old. Int J Endocrinol. 2013;2013:942030. doi: 10.1155/2013/942030. Epub 2013 Dec 8. PMID: 24382963; PMCID: PMC3870652.;

[4] Tavares AB, Micmacher E, Biesek S, Assumpção R, Redorat R, Veloso U, Vaisman M, Farinatti PT, Conceição F. Effects of Growth Hormone Administration on Muscle Strength in Men over 50 Years Old. Int J Endocrinol. 2013;2013:942030. doi: 10.1155/2013/942030. Epub 2013 Dec 8. PMID: 24382963; PMCID: PMC3870652.;

[5] Sinha DK, Balasubramanian A, Tatem AJ, Rivera-Mirabal J, Yu J, Kovac J, Pastuszak AW, Lipshultz LI. Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males. Transl Androl Urol. 2020 Mar;9(Suppl 2):S149-S159. doi: 10.21037/tau.2019.11.30. PMID: 32257855; PMCID: PMC7108996.;