Ketamine Nasal Spray Ketamine Nasal Spray

Ketamine Nasal Spray

$399
Our self-administered Ketamine Nasal Spray offers rapid relief for treatment-resistant depression with potential benefits including reduced depressive symptoms, improved mood stability, decreased suicidal thoughts, and enhanced response when combined with therapy.
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What is Ketamine 
Nasal Spray?

What is Ketamine 
Nasal Spray?

What is Ketamine 
Nasal Spray?

Ketamine Nasal Spray is an innovative treatment for individuals struggling with treatment-resistant depression (TRD)—a form of depression that does not respond to standard antidepressants. Unlike traditional medications that can take weeks to work, ketamine (including racemic ketamine and esketamine) targets NMDA receptors in the brain, improving synaptic connections and enhancing mood-regulating pathways.

Esketamine, the FDA-approved form of ketamine nasal spray, has shown clinical benefits as early as 24 hours, while racemic ketamine – used off-label -has also demonstrated significant reductions in depressive symptoms.

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Best uses for Ketamine Nasal Spray

Treatment-Resistant Depression

Treatment-Resistant Depression

For individuals who have not responded to standard antidepressants, ketamine nasal spray offers rapid symptom relief and a new path forward.
Suicidal<br /> Thoughts

Suicidal
Thoughts

Racemic ketamine has shown reductions in acute suicidal ideation, providing urgent support when timely intervention matters most.
Adjunct to<br /> Therapy

Adjunct to
Therapy

Ketamine can be combined with therapy or antidepressants to enhance outcomes, helping patients achieve sustained mood improvement.
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Ordering is easy and convenient

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  • Medical Evaluation

    Meet with a licensed clinician to determine if ketamine nasal spray is right for you.

  • Receive shipment

    Your Ketamine Nasal Spray is delivered directly to your door.

  • Self-administer

    Follow your personalized treatment plan with guided support from our medical team.

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Frequently asked questions

What is ketamine nasal spray used for?


Ketamine nasal spray is primarily used for treatment-resistant depression, especially in individuals who have not found relief with standard antidepressants. It may also reduce suicidal thoughts and improve outcomes when used alongside therapy.

How quickly does ketamine nasal spray work?

Unlike traditional antidepressants that may take weeks, ketamine nasal spray can show results within 24 hours. Some patients experience improved mood, energy, and outlook after their first dose.

Is ketamine nasal spray safe?

When prescribed and monitored by a medical provider, ketamine nasal spray is generally well-tolerated. Side effects may include dizziness, nausea, or dissociation, but these are typically temporary. ConciergeMD ensures structured safety monitoring for every patient.

What’s the difference between esketamine and racemic ketamine?
Esketamine is the FDA-approved nasal spray for treatment-resistant depression, administered under strict safety protocols. Racemic ketamine is used off-label and has also shown rapid antidepressant effects. Both forms act on NMDA receptors to boost brain connectivity.
How do I know if I’m a candidate for ketamine nasal spray?

You may be a candidate if you have major depressive disorder that has not responded to at least two antidepressant medications. ConciergeMD’s medical evaluation will determine eligibility and the best treatment approach.