glass bottle of peptide

What Is Ipamorelin?

Peptides are small proteins made up of amino acids that may have muscle-building, anti-inflammatory, and anti-aging properties. Today, we discuss how ipamorelin – one type of peptide – can help you improve your overall health and wellness.

What is Ipamorelin?

Ipamorelin is a type of growth hormone-releasing peptide (GHRP) that stimulates the secretion of growth hormones in the body. 

This peptide was first investigated as a potential treatment for postoperative ileus, a condition that can lead to bowel obstruction because it causes the bowels to stop working after an individual has undergone bowel surgery.

There is limited clinical research on the effects of ipamorelin, but animal research shows potential for treating growth disorders such as childhood growth hormone deficiency. It may also help promote muscle growth, increase bone density, and improve sleep quality.

hand with glove holding an injection piercing a vial with fluid

Unlike other GHRPs, this peptide has a targeted effect on the body’s natural growth hormone release, making it a drug-free option for patients who want to improve their overall health and wellness.

Benefits and Uses of Ipamorelin

Here, we will explore the benefits and uses of ipamorelin, including in sports, anti-aging and wellness, and general diagnostics.

Sports

The peptide CJC-1295 works with ipamorelin to help reduce body fat by promoting lipolysis, or fat breakdown.

man flexing his tricep muscule

Both of these peptides can also help:

In addition to aiding weight loss, ipamorelin may help:

It may also lower your blood pressure and help you sleep better. All of these effects are beneficial for athletes wanting to improve their performance and endurance.

Ipamorelin is popular among bodybuilders because it stimulates the production of growth hormone by mimicking the hormone ghrelin and helping produce high levels of insulin-like growth factor-1 (IGF-1). IGF-1 is necessary for muscle mass growth, and it helps to improve bone and muscle strength which can support overall improvements in body composition.

Anti-Aging and Wellness

As you age, your body processes slow down. Aging leads to issues such as:

  • joint pain
  • mental decline
  • changes in the quality and strength of the skin
  • and reduced bone density.

Additionally, it simultaneously becomes harder to lose weight and easier to gain it.

Many peptides address anti-aging properties that improve the strength and appearance of hair, nails, and skin, but ipamorelin can address more than just the skin-deep effects of aging.

Anti-aging benefits of ipamorelin may include:

  • Improved appearance and strength of hair and skin
  • Improved cardiovascular system
  • Improved cell regeneration rates
  • Improved mental clarity and cognitive functioning
  • Improved recovery time
  • Increased muscle mass
  • Reduced body fat
  • Reduced joint and muscular pain
  • Strengthened bones
  • Strengthened immune system
beautiful hair

What can you expect from treatment?

The effects of peptide supplementation typically occur gradually, so it can take time for you to begin seeing results after you begin ipamorelin injections.

  • After one month of treatment, you may experience a night of better and sound sleep, feel more refreshed when you wake up, improved stamina, increased energy, and a more optimistic attitude.
  • During the second month, you may experience better digestion and eyesight (especially night vision), enhanced sexual function, improved muscle tone, improved nail growth, improved skin tone, increased strength, and weight loss.
older couple practising yoga
  • During the third month, you may notice alleviation of some menopause symptoms, faster wound healing, greater body flexibility, less muscle soreness, increased hair growth, increased sexual desire, improvement in mental processes, less pain, and a reduction in premenstrual syndrome (PMS) symptoms.
  • During the fourth month, you may experience weight loss, thickening of the skin and greater elasticity, improvement in skin texture and appearance, reduced visibility of wrinkles, and thickening of hair with increased shine.

Safety and Side Effects

Ipamorelin is well-tolerated and generally considered safe when it is used as directed, but there are some potential side effects to be aware of.

The most common side effects of ipamorelin are:

  • Flushing (reddening of the skin and a warm sensation on the skin)
  • Headaches
  • Nausea

Less common side effects include:

  • Abdominal pain
  • Dizziness
  • Fatigue

It is not known what the long-term side effects of ipamorelin are. You should contact a doctor if you experience any adverse reactions.

How is ipamorelin given?

Ipamorelin is given in the form of a subcutaneous (under the skin) injection that you can administer yourself.

You will need to wash your hands before administering the injection on clean skin in the stomach or abdominal region. Only use sterile needles and syringes. Properly dispose of the used needle and wash your hands again after you administer the injection.

Ipamorelin should only be used as directed under the guidance of your doctor. They will be able to inform you if this peptide is a good option for you based on your overall health. Be sure to let your doctor know about the medication you take before you begin treatment to avoid medication interactions.

Young woman injecting herself

Conclusion

Ipamorelin is a growth hormone-releasing peptide that offers many potential benefits for health and wellness. It stimulates the release of growth hormone from the anterior pituitary gland, which may influence pain relief and regulate bodily growth, thyroid function, and body temperature.

If you want to experience the maximum benefits of ipamorelin injections (especially in regard to weight loss, muscle gain, and recovery), it is important that you pair ipamorelin injections with daily exercise, an adequate amount of good sleep each night, and eating a healthy, balanced diet that includes plenty of carbs, fats, and proteins. You must also stay well hydrated by drinking plenty of water. Taking supplements like BCAAs, creatine, and glutamine may also enhance the effects of the ipamorelin injections.

Ipamorelin is not FDA-approved and is not regulated for safety and quality the way that prescription medications are. With this in mind, it is crucial that you only use this peptide under medical supervision and in the appropriate dosage given to you by your doctor.

Peptide Shots - Frequently Asked Questions

What is included in our peptides injections?

There are many different peptide injections that we offer as part of a peptide therapy including Sermorelin, GHK-CU and PT-141.

What is SERMORELIN?

Sermorelin is a synthetic form of GHRH (growth hormone-releasing hormone) which controls the hGH (human growth hormone) and it’s recommended to people who have low levels of hGH. 

How do peptides improve your sleep?

Serotonin is a neurotransmitter present in the brain that releases chemicals as messages to your brain and body that it is time to go to sleep. Some peptides can interact with serotonin. Serotonin regulation issues can definitely interfere with a person's ability to have a good night's sleep.

Sermorelin is recognized for their potency as peptides that enhance sleep.

How do peptides improve immune health?

The immune response can be either blocked or stimulated to produce tolerance using peptides and peptidomimetics as immunomodulating agents.

Read more: Peptide Shots FAQ

References

[1] The GH secretagogues ipamorelin and GH-releasing peptide-6 increase bone mineral content in adult female rats;