glutathione chemical formula

How to Notice if You Have Glutathione Deficiency

woman holding her head like she has a headache

Glutathione deficiency can have many signs, some of which are not obvious at first glance, so knowing the low glutathione symptoms can help you get the treatment you need to live your best life possible. First, you’ll learn what Glutathione is and why it’s so important to the human body. Then you’ll learn about all the different ways your body can show that it needs more Glutathione, so you can determine whether or not you have glutathione deficiency yourself.

Glutathione Deficiency

Glutathione deficiency can be quite serious, so it’s important to recognize the glutathione deficiency symptoms before it’s too late to address them. Glutathione deficiency is linked to various diseases and illnesses. Some diseases associated with low glutathione may include seizures, intellectual disability, loss of coordination, and more. It’s not always easy to tell if you have glutathione deficiency or not, but some very common symptoms of low glutathione can give you an idea if your body needs more.

Glutathione is the master antioxidant because it protects your body from oxidative stress caused by toxins and free radicals, so it’s important to keep up with your intake of foods high in glutathione or glutathione precursors.1 The word glutathione deficiency (or insufficiency) may sound like some new-age thing. Still, in reality, it’s something that’s affecting millions of people every day and might even be affecting you.

Common Low Glutathione Symptoms

It’s important to watch for signs of glutathione deficiency because, when left untreated, reduced glutathione levels can cause serious long-term problems in your health. Here are a few indicators that you might be suffering from a glutathione deficiency:

NAD for fatigue
  • Frequent infections like colds or flu
  • Difficulty managing weight

If you suspect that you might be suffering from glutathione deficiency, then there are a few ways for you to test whether or not your body needs more Glutathione.

Doctors usually assess antioxidant status by measuring Glutathione concentration per gram of hemoglobin in red blood cells. Although it isn’t easy to find reliable information about optimal levels as ideal test results vary depending on age, gender, etc.

Monitoring Glutathione

Our body naturally makes Glutathione from three amino acids: cysteine, glycine, and glutamate. When making enzymes or proteins, cells use up most of your available cysteine supplies. The remaining glutamate and glycine combine with B vitamins and selenium to produce Glutathione.

Our diet plays a significant factor in these levels. In more severe cases, glutathione deficiency treatments will focus on administering Glutathione directly into the bloodstream through an IV infusion. In extreme cases such as chronic glutathione depletion or where someone has been exposed to large amounts of toxins over a long time – such as those who work with pesticides – injections will become a daily treatment until their levels normalize again. In any case, dietary intakes from fruits and vegetables must be adequate for normal enzymatic reactions associated with the synthesis and metabolism of Glutathione. Inadequate intake or digestion can result in a reduced body pool or lack of protection from oxidative stressors, which might increase the risk for chronic disease over time.

herbs and pills in cups and bowls

Types of Glutathione Supplements

If your body is deficient in Glutathione, it can be difficult to determine. Symptoms of Glutathione deficiency are subtle and often mistaken for other conditions. Any signs or concerns must be addressed, so they don’t become more significant problems down the road.

One way to treat it is by taking glutathione supplements under your doctor’s supervision. There is also some evidence that eating foods rich in Glutathione such as:

  • Grapefruit
  • Broccoli
  • Papaya
  • Pineapples
  • Cauliflower
  • Corn
  • Cabbage
  • Green peppers

These can help give your body what it needs to maintain proper levels of GSH. Another way to boost production is with a sulfur supplement such as whey protein or N-acetylcysteine.

Companies like Drip Hydration offer at-home IV therapy treatments. Their NAD+ Boost is full of super vitamins that create a unique blend to supercharge effectiveness.

Get Glutathione IV Therapy

Glutathione is a powerful antioxidant that can help boost your immune system, support energy levels, and improve your mood. Treatments are more accessible than ever with nearby locations and flexible scheduling.

Glutathione is included in many of our treatments, including:

  • Immune Boost IV
  • Super Immune Boost IV
  • Recovery IV
  • Beauty IV
  • All-Inclusive IV
  • Glutathione Push (A single shot containing a supercharged dose of glutathione)

Schedule your appointment with our medical team to start your journey to a healthier, happier self.

Glutathione - Frequently Asked Questions

What is glutathione?

Glycine, cysteine, and glutamic acid are the building blocks for the compound glutathione. It is created by the liver and is used by several bodily functions. Glutathione helps with the production of chemicals and proteins required by the body, as well as immune system activity.

What are the benefits of taking glutathione?

Taking glutathione has many benefits including:

  • Reducing oxidative stress
  • Reducing cell damage in alcoholic and nonalcoholic liver disease
  • Improves insulin resistance in older people
  • Increase mobility for people with peripheral artery disease
  • Reduces symptoms of Parkinson’s disease
  • Might help fight autoimmune diseases
  • Might reduce oxidative damage in children with autism
  • Might reduce the impact of uncontrolled diabetes
  • Might reduce respiratory disease symptoms
  • Might improve psoriasis

Does glutathione help reduce oxidative stress?

According to one research, glutathione either increases or decreases the body's immune response, which helps alleviate oxidative stress. Diseases with an autoimmune component damage particular cells' mitochondria. By scavenging free radicals, glutathione protects the mitochondria of the cell.

Glutathione IV Therapy vs supplements

Glutathione supplementation has been related to digestive problems, such as bloating or stomach cramps. Intravenous glutathione provides the antioxidant directly to your cells by totally avoiding the digestive system.

Glutathione for heavy trauma recovery

Glutathione is a powerful antioxidant that can help protect cells from damage caused by free radicals, which can be caused by heavy trauma. However, the body's ability to produce Glutathione may be impaired by heavy trauma, and additional Glutathione may be needed to support the body's natural healing processes. It is important to consult with a healthcare provider to determine the most appropriate treatment for heavy trauma recovery.

What are the differences between Glutathione and NAC?

Glutathione and N-acetylcysteine (NAC) are both natural compounds with antioxidant properties. However, they differ in the way they are used by the body and in their potential health benefits. Glutathione is a tripeptide naturally produced by the body, while NAC is a precursor to Glutathione that can be taken as a supplement. Glutathione is known for its ability to support the immune system and protect against cell damage, while NAC is primarily used to support respiratory health and may have potential benefits for mental health.

What is Liposomal Glutathione?

Liposomal glutathione is a form of the antioxidant glutathione that is encased in liposomes. Liposomes are tiny spheres made of phospholipids, the same material that makes up the cell membrane. The liposomes protect the glutathione and allow it to be absorbed more efficiently into the body.

Can you combine vitamins with Glutathione?

Combining vitamins with glutathione may help to ensure that the body has sufficient levels of these nutrients to support optimal health. Some studies have suggested that the combination of vitamins with glutathione may have specific health benefits. For example, some research has found that this combination may help to support healthy brain function and protect against cognitive decline. Other studies have suggested that the combination may help to support healthy liver function and protect against liver disease.

What are the signs of Glutathione deficiency?

Some of the most common signs of glutathione deficiency include fatigue, muscle weakness, and difficulty exercising. A deficiency of glutathione may also cause the skin to become dry and flaky, and may contribute to the development of skin conditions such as eczema.

Additionally, a deficiency of glutathione may impair the immune system, making the body more susceptible to infections and diseases. Some people with a deficiency of glutathione may experience increased susceptibility to colds and flu, and may develop chronic infections more easily.

Furthermore, a deficiency of glutathione may affect the liver, leading to liver damage and potentially contributing to the development of liver disease. Some people with a deficiency of glutathione may experience symptoms such as jaundice, in which the skin and whites of the eyes become yellow.

How does Glutathione help skin health?

Glutathione is a natural compound found in the body that plays a crucial role in maintaining skin health and appearance. It is an antioxidant that helps protect the skin cells from damage caused by free radicals, which can lead to premature aging and skin conditions such as acne, eczema, and psoriasis. Glutathione also helps to maintain an even skin tone and can improve the overall appearance of the skin by making it look brighter and more youthful. In addition, it can help to reduce the appearance of dark spots and blemishes, giving the skin a more even and radiant appearance.

What IV therapy blends include Glutathione?

We have quite a few IV Therapy blends that contain glutathione including: Immune Boost, Recovery IV Treatment, Super Immune Boost, All-Inclusive IV Treatment, NAD+ Boost, and Beauty IV Treatment.

How does Glutathione help with liver health?

Glutathione is a powerful antioxidant that helps to protect the liver from damage caused by toxins, such as alcohol and other harmful substances. Glutathione also helps to break down these toxins, making them easier for the liver to process and eliminate from the body. In addition, glutathione plays a key role in supporting the overall health and function of the liver, helping to keep it working properly and efficiently.


[1] Pizzino G, Irrera N, Cucinotta M. et al. - Oxidative Stress: Harms and Benefits for Human Health. Oxid Med Cell Longev.;