Nicotinamide adenine dinucleotide (NAD) is an essential cofactor and coenzyme that participates in crucial biochemical processes in the body. Scientists believe its functions are linked to the aging process and that a decline in NAD levels can be the reason our bodies age.
NAD therapy replenishes the amount of NAD in the body, slowing down the aging process and providing cells with the materials they need to operate at a youthful level. The resulting benefits of NAD therapy are manifold, including mood improvement, increased energy, improved mental clarity, and better memory and concentration. Beyond NAD’s visible effects, what happens at a cellular level, and what is the difference between NAD, NAD+ and NADH?
NAD's Role in Your Metabolism
NAD works on mitochondria and increases the length of telomeres, which are the protective caps located at the ends of chromosomes that become shorter as the body ages. NAD increases the activity of SIRT1 and PARP 1 proteins, which are linked with a slower rate of aging and influencing DNA repair respectively. – source
The oxidation and reduction process
The body generates energy through the transfer of electrons, which is also the basis of all chemical reactions. When electrons change hands, it creates different molecules while generating energy in a process called oxidation and reduction.
Think of oxidation and reduction as an exchange of batteries. One molecule has batteries that another molecule needs. But they need an intermediary to help them swap batteries. In this case, cofactors like NAD step in.
However, the role of oxidation-reduction extends beyond just power generation. In some cases, the process can help ‘disarm’ free radicals (charged molecules that can harm the cell) or modulate cellular and metabolic signaling pathways.1
With this basic understanding of the oxidation and reduction process, here’s how NAD fits into the picture.
NAD
NAD is the general name used to describe all types of nicotinamide adenine dinucleotide. It is a catch-all term used when referring to NAD, NAD+ or NADH.
However, although this may be the case for general references, most scientific references will strictly use NAD+ or NADH because each term describes the actual molecule under reference.
NAD+ is the oxidized form of NAD and is the precursor to most chemical reactions involving NAD.
What does oxidized mean?
An oxidized molecule has a chemical structure that can accept electrons from another molecule. NAD+, therefore, has a chemical structure that can accept electrons from other molecules, helping catalyze reactions in multiple biological processes.
During NAD IV therapy, NAD+ is administered because it is the biologically functional form that has catalytic properties.2 When it gets into the bloodstream, cells can immediately use this form of NAD to power their various processes.
However, once NAD+ has accepted electrons, its state changes, becoming a reduced form of NAD that is called NADH.
NADH
NADH stands for nicotinamide adenine dinucleotide (NAD) + hydrogen (H). As the name suggests, it is a NAD molecule that has accepted electrons (in this case, through hydrogen atoms), becoming the reduced form of NAD.
What does reduction mean?
A reduced molecule has a chemical structure that has accepted extra electrons from another molecule. NADH, therefore, has a chemical structure that has accepted two hydrogen atoms (with its electrons), completing the catalytic oxidation-reduction process of NAD.
The NAD+ NADH cycle
Combining the two processes creates the NAD+/NADH oxidation-reduction chain.
Here’s how the process works:
NAD+ enters the cell or organelle (like mitochondria), accepts electrons in the form of hydrogen atoms from NADH (remember it has some extra electrons to donate), and becomes NADH.3 Meanwhile, the NADH that donated electrons becomes NAD+, and the process repeats itself.
NAD+ and NADH are simply different forms of NAD, one with extra electrons and one without, and they pass these electrons back and forth between themselves as a catalytic chain reaction.
This coupled reaction explains why, when NAD+ levels fall, the entire chain reaction starts to fail. Similarly, replenishing NAD+ levels via IV infusion helps restore these reactions to optimum levels.
Oral NAD vs. IV NAD
The details above demonstrate the importance of maintaining optimum levels of NAD+ in the body. Taking NAD via oral supplements and IV does increase NAD+ levels, but not equally. Here’s why.
When you take oral NAD supplements, the NAD must pass through your gut and find its way to your bloodstream and then to the cells that need it. Along the way, a significant amount of NAD is lost due to issues like gut absorption, gut emptying rate, cardiovascular health, and others.
On the other hand, receiving a NAD IV infusion bypasses all these hurdles, delivering NAD to your bloodstream, an expressway to your cells that guarantees 100% absorption.
Take the First Step towards Better Health with NAD Therapy
Take control of your health and address your biggest health concerns with NAD therapy. Consult with a trusted medical professional today to explore the potential benefits of NAD and find personalized solutions for your unique needs.
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Transform your health with NAD therapy and experience the life-changing benefits of personalized treatment tailored to your unique needs.
NAD is a coenzyme that is naturally produced by the body and is essential for various physiological processes, including energy production and DNA repair. It is found in all living cells and plays a critical role in many of the body's metabolic processes. NAD is a dinucleotide, which means that it consists of two nucleotides joined together. It is made up of two molecules: nicotinamide and adenine, which are joined together by a phosphate group. NAD is involved in a wide range of biological processes, including the metabolism of carbohydrates, proteins, and fats, and is essential for the proper functioning of the body's cells and tissues. Our nurse will arrive at your location of choice with all the equipment necessary for the appointment. They will then administer the IV into your arm and stay with you to monitor the treatment and answer any questions you may have. Our NAD IV treatments generally last couple of hours per session. You can sit back, watch a movie or a favorite show, browse social media, or even work while the treatment is in progress. Drip Hydration brings appointments directly to you whether you are at home, at a hotel, or at the office. We make getting at home NAD IV treatments easy and convenient, saving you the time and hassle of sitting in traffic or waiting in a clinic. You don’t have to wait until you are experiencing a medical condition to enjoy the benefits of NAD IV therapy. NAD plays a role in hundreds of chemical functions throughout your body. This versatile treatment helps promote whole-body wellness and can help your body maintain optimal performance over time. IV therapy in general is FDA approved. Our nurses are overseen by our Medical Director, Abe Malkin, and every nurse is registered and certified per state standards. NAD is considered a dietary supplement, not a drug. The FDA does not currently evaluate dietary supplements in their current regulations. However, NAD is well-tolerated, meaning that there are rarely side effects. Our IV NAD treatments take couple of hours to administer per session. The number of sessions vary by individual and will be determined during your initial consultation. Some studies have suggested that NAD may have anti-aging effects by helping to support the production of enzymes that are involved in DNA repair and maintenance, which are essential for maintaining healthy cells and tissues. Additionally, NAD may support the production of enzymes that are involved in the body's natural detoxification processes, which can help to reduce the effects of oxidative stress and support healthy aging. Some studies have suggested that NAD may support healthy metabolism by helping to regulate the body's energy production and utilization, and may also support the production of enzymes that are involved in various metabolic processes. Additionally, NAD may support the body's natural detoxification processes, which are important for maintaining overall health and wellness. NAD IV treatments are most effective when used over time. You can get treatments several times per month unless you are otherwise advised during your initial consultation. Following a NAD IV drip, most patients feel more energetic, clearer-headed, and focused. Regular treatments may improve these effects over time. Not at all! You can resume your normal activities immediately after your appointment. Where do you deliver NAD IV treatments? Drip Hydration delivers NAD IV treatments anywhere within our service areas, which you can find on our service area pages. That said, we recommend choosing a comfortable place for NAD treatments since this type of IV couple of hours per appointment. IV NAD is delivered directly into your bloodstream, where it becomes available to your cells for immediate use. Because NAD bypasses the digestive and metabolic systems, you can expect a 100% absorption rate for maximum effect and minimal waste. Oral NAD supplements, on the other hand, must pass through your digestive system, where they are partly metabolized before your body has access to orally given NAD. There are two main differences between a NAD IV and a Vitamin Drip: duration and ingredients. NAD IVs generally take couple of hours to administer per session while vitamin drips take 30 - 45 minutes. Our vitamin drips are specially blended to improve a variety of symptoms and ailments. Our NAD+ Boost treatments contains vitamins that can help make this IV more effective with longer-lasting effects. No, you do not need any special supplies. Our nurse will bring everything needed for the appointment. NAD is believed to have potential benefits for brain health and function, although more research is needed to fully understand its effects. Some studies have suggested that NAD may have neuroprotective effects, meaning that it may help to protect the brain from damage and support healthy brain function. Additionally, NAD may support the production of neurotransmitters, which are chemicals that help to transmit signals between the brain's cells, and may help to improve cognitive function and memory. NAD injection therapy is believed to have several potential benefits, including improving energy levels, supporting cognitive function, reducing inflammation, and supporting the body's natural detoxification processes. Additionally, NAD injection therapy is often used in combination with other treatments, such as IV vitamin therapy, to support the body's natural recovery processes and improve overall health and wellness. The main difference between NAD injection and NAD IV therapy is the method of delivery. NAD injection involves injecting NAD directly into the bloodstream using a syringe, while NAD IV therapy involves infusing NAD into the bloodstream through a small tube that is inserted into a vein. The main difference between NAD injections and NAD supplements is the method of delivery. NAD injections involve injecting NAD directly into the bloodstream using a syringe, while NAD supplements are taken orally in the form of pills or capsules. When administering the injection, it is important to use a clean, sterile needle and syringe, and to inject the NAD into a vein using a slow, steady motion. It is also important to properly dispose of the used needles and syringes to avoid the risk of injury or infection. It is also important to carefully follow the instructions provided by the healthcare professional and the manufacturer of the NAD injection, including proper storage and handling of the injection and any necessary preparation steps. NAD+ nasal spray is believed to have several potential benefits, including improving energy levels, supporting cognitive function, reducing inflammation, and supporting the body's natural detoxification processes. The main difference between NAD injection and NAD+ nasal spray is the method of delivery. NAD injection involves injecting NAD directly into the bloodstream using a syringe, while NAD+ nasal spray involves delivering NAD directly into the bloodstream through the nose. The primary distinction between NAD+ nasal spray and NAD supplements is the route of administration. NAD+ nasal spray delivers NAD directly into the bloodstream via the nose, whereas NAD supplements are taken orally as tablets or capsules. The frequency of NAD+ nasal spray use will depend on the specific product and the individual's needs and preferences. It is important to consult with a healthcare professional to determine the appropriate frequency of NAD+ nasal spray use, as well as any potential risks or side effects. In general, NAD+ nasal spray can be used daily or as needed, depending on the individual's goals and needs. It is also important to carefully follow the instructions provided by the healthcare professional and the manufacturer of the NAD+ nasal spray, including any recommended dosing guidelines and precautions. The effects of NAD+ nasal spray may vary depending on the individual and their unique physiology and health needs. In general, people may experience improved energy levels, cognitive function, and overall health and wellness after using NAD+ nasal spray. Additionally, NAD+ nasal spray may help to support the body's natural recovery processes and reduce the symptoms of conditions such as chronic fatigue syndrome, fibromyalgia, and addiction.NAD - Frequently Asked Questions
What is NAD?
What can I expect during a NAD IV treatment?
What sets Drip Hydration apart from other NAD IV treatment providers?
Is NAD right for me?
Is IV therapy FDA approved?
Is NAD safe?
How long do IV treatments take?
Does NAD help battle aging?
Does NAD Improve metabolic function?
How often can I get an NAD treatment?
What can I expect to feel after a NAD IV drip?
Is there any downtime or recovery after a NAD drip?
How is IV NAD better than an oral NAD supplement?
What is the difference between a NAD IV and a vitamin drip?
Do I need any special supplies for my NAD IV appointment?
Does NAD improve brain health and function?
NAD Injection Therapy
What are the benefits of NAD Injection Therapy?
What is the difference between NAD injection vs NAD IV therapy?
What is the difference between NAD injections and NAD supplements?
How to best self-administer a NAD injection?
NAD+ Nasal Spray
What are the benefits of NAD+ nasal spray?
What is the difference between NAD injection and NAD+ nasal spray?
What is the difference between NAD+ nasal spray and NAD supplements?
How often can I use the NAD+ nasal spray?
What can I expect to feel after using the NAD+ nasal spray?
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