NAD IV Therapy for Drug Addiction Rehab & Recovery

Withdrawal symptoms are one of the biggest reasons for relapse during addiction treatment. NAD, a coenzyme that plays a significant role in cellular health and energy metabolism, may reduce the severity of withdrawal symptoms and help repair damage caused by substance abuse. When used alongside traditional addiction recovery treatments, in-home NAD infusions may help you overcome addiction for good.

Let’s take a closer look at how NAD can be an invaluable ally in your addiction recovery journey.

NAD's Role in Your Metabolism

NAD works on mitochondria and increases the length of telomeres, which are the protective caps located at the ends of chromosomes that become shorter as the body ages. NAD increases the activity of SIRT1 and PARP 1 proteins, which are linked with a slower rate of aging and influencing DNA repair respectively. – source


  • Drug addiction is a chronic disease in which an individual cannot control when or how often they seek out and use substances such as opiates, alcohol, and nicotine.
  • Drug addiction rehabilitation is not a single treatment, but consists of a combination of therapies that address not only the addiction itself, but the behaviors and triggers that lead to relapse.
  • Relapse is one of the most challenging aspects of reaching a successful rehabilitation outcome.
  • Nicotinamide adenine dinucleotide (NAD) IV treatments can help you beat addiction and avoid relapse. NAD helps relieve the symptoms of withdrawal, reduces cravings, detoxifies your body, and repair cellular damage from long-term drug use. [1]
  • At-home IV NAD for addiction treatments are not a ‘magic bullet’, but work instead as a convenient and valuable co-therapy when used alongside traditional drug rehab treatments.

Understanding Drug Addiction

Drug addiction is not a new problem, but overdose deaths from opioids—including prescription opioids, heroin, and synthetic opioids such as fentanyl—have increased almost six times since 1999.2

The latest numbers from the Centers for Disease Control and Prevention (CDC) show that today, two out of three (66%) drug overdose deaths involve an opioid, which are substances that work in the nervous system of the body or the brain to reduce the intensity of pain. More than 47,000 people died in 2017 from overdoses involving opioids. More than one third of those deaths (36%) involved prescription opioids.1 As a result of these alarming trends, there is a heightened interest on how effective and speedy drug addiction recovery can be achieved.

cash, syringe and a spoon with tablets and pills on a table

Before tackling drug addiction recovery, in yourself or in someone whom you care for, it is important to understand addiction and what it entails. Here’s how the National Institute on Drug Abuse defines addiction:

Drug addiction is a chronic disease characterized by compulsive, or uncontrollable, drug seeking and use despite harmful consequences and changes in the brain, which can be long lasting. These changes in the brain can lead to the harmful behaviors seen in people who use drugs. Drug addiction is also a relapsing disease. Relapse is the return to drug use after an attempt to stop.

Substance addiction—whether it is to prescription drugs, illegal drugs, alcohol or tobacco—is complex because it affects both our brain function and behavior. Addiction is a chronic, but treatable disease and needs to be acknowledged as such. This is a critical first step in the addiction recovery process.

It is important to remember that addiction recovery has no single ‘right’ treatment method. An effective treatment method needs to address all of an addicted person’s needs, going beyond the drug abuse. This is why it is such a challenge to many.

Treatments for Drug Addiction

These options, most often in combination with others, have been successful for treating drug addiction:

  • Behavioral counseling – Behavioral counseling is a type of therapy that focuses on modifying negative behaviors and developing positive ones. It involves identifying patterns of behavior and implementing strategies to change them.
  • Medications – for withdrawal, relapse prevention and for co-occurring conditions such as anxiety and depression.
  • Medical devices and applications for treating withdrawal symptoms or to deliver skills training
  • Evaluation and treatment for co-occurring mental health issues including anxiety and depression
two people consoling a man in a gym during an anonymous meeting for addicts
  • Long-term follow-up to ensure there is no relapse plus IV therapy. For best effect though, it is necessary to combine this therapy with other options available for drug addiction treatment. It is also important to understand why the majority of people relapse when seeking treatment for drug addiction.

Successful drug addiction treatment requires a range of care comprising a tailored treatment program and follow-up options. Addiction treatment should include both medical and mental health services where necessary as well as follow-up. See diagram for the components of a comprehensive drug addiction treatment.

If you are intent on quitting, going cold turkey on your addiction is easier today than ever thanks to NAD therapy.

Understanding Drug Addiction Relapse

Drug addiction is characterized by intense drug cravings and an inability to control drug use even though people know about its many negative consequences.

Relapse during drug addiction treatment is common. Studies show that more than 85 percent of people in addiction treatment relapse and return to drug use within the year following treatment. Yes, that is more than 8 out of 10. According to researchers’ estimates more than two thirds of people in recovery relapse within weeks to months of beginning their addiction treatment.3 Recent research on drug relapse prevention also suggests that, we should view relapses during recovery as a result of an underlying process, rather than as random events.4

unconscious man on the floor

Relapse should be considered as a part of overall recovery process. The National Institute on Drug Abuse defines relapse as “a series of setbacks along the way to recovery”. As such, we should look upon relapses as part of the recovery process, instead of as failures to recover.

This is why a long-term drug relapse prevention plan is essential to cure your addiction and to stay clean. The reality is that most people will be unsuccessful in their first attempts to stay drug free. This is where a solid long-term plan is critical for long term success.
Drug relapse prevention can teach you effective techniques for preventing relapse and how you can manage reoccurrence. This is where understanding drug relapse warning signs matter.

Spot Drug Relapse Warning Signs

Drug relapse warning signs can be divided into three groups:

During the emotional stage of your relapse, you may not be consciously thinking about drug use again, but you sure are setting yourself up for it emotionally.

You may observe these emotional aspects in yourself: You isolate yourself and may stop going to treatment sessions or meetings. When you show up at meetings you may not share your feelings and bottle up your emotions. Your eating and sleeping habits will begin to turn again for the worse. You’ll stop taking care of yourself mentally or physically. But you’ll also be in denial that you may be going into relapse. You will also see yourself relaxing self-imposed rules you have been sticking to since giving up drugs.

Once you enter the mental relapse stage, you actually begin thinking about drugs again. Drug cravings will return and you will begin romanticizing your past drug use. You begin thinking of people and places you’ve associated when you were previously using drugs. You can catch yourself minimizing the consequences of drugs, bargain with yourself about it and begin lying to others. Eventually this phase comes down to thinking about how you can better control your drug use next time, planning your relapse or seeking for opportunities to do drugs. You will experience the inner conflict within you, of wanting to use drugs and wanting to stay clean. After a while, this inner struggle wears you down and you enter the physical relapse stage.

In the physical relapse stage, you go back to using drugs. You may justify this by saying it is for just once, and then end up with uncontrolled drug use. As you may know already, this is the hardest stage to come back from.

What is NAD+?

Nicotinamide adenine dinucleotide, known as NAD+ for short, is a critical coenzyme that powers metabolic processes in living cells. It helps in a variety of biological processes including:

NAD+ increases your body’s levels of serotonin – a neurotransmitter associated with mood regulation–and helps improve symptoms of depression and anxiety.

NAD+ is helpful for individuals undergoing substance abuse therapy and addiction recovery. While NAD+ is also available as an oral supplement, it is far more effective when absorbed directly into the bloodstream by way of IV therapy. NAD administered intravenously helps significantly reduce drug cravings and help manage withdrawal symptoms.

nurse preparing an IV

NAD+ and Dealing with Cravings

Cravings are a common factor that disrupts drug addiction recovery programs. It is difficult to give up drugs, alcohol and other addictive substances because of the cravings you experience when trying to give it up. This is where NAD+ becomes an invaluable tool in your effective drug recovery arsenal.

Research shows that NAD also helps significantly lessen the effects of withdrawal. This is why it has been used in IV form since the 1960s to treat withdrawal from a variety of drugs and alcohol. NAD+ helps reduce the severity of drug cravings significantly and thereby reduce relapse episodes even beyond 12 to 20 months post treatment.5

NAD Limitations and How to Overcome Them

One limitation of NAD is that NAD+ IV alone cannot make up the entire drug recovery treatment. But there is a lot of research that shows how this limitation can be overcome.

To make drug addiction recovery with NAD+ IV treatment more profound, complete and lasting, it is combined with specified amino acids. There is also evidence that amino acid based IV supplementation helps in the recovery process.6 A study published in the Biomed Research International journal in 2017 found that red blood cells loaded with alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALD) can metabolize plasma ethanol and acetaldehyde, but does so with low efficiency.7 An investigation into rate-limiting factors in ethanol oxidation using IV experiments on humans and simulations showed that NAD+ generation rate in red blood cell glycolysis, is the rate-limiting step in external ethanol oxidation. The rate of oxidation could be increased if red blood cells are supplemented by NAD+ and pyruvate using the one-step procedure of hypoosmotic dialysis.

Blood cells loaded with ADH, ALD, NAD+, and pyruvate were able to metabolize ethanol 20-40 times faster than reported in previous studies. Scientists concluded that the “transfusion of the RBCs loaded with the complete metabolic system, including ADH, ALD, pyruvate, and NAD+ in the patients with alcohol intoxication, may be a promising method for rapid detoxification of blood alcohol based on metabolism.”

There’s also evidence that treatments comprising IV infusions of NAD, together with vitamins and oral amino acids among other substances, is an effective detox treatment for alcohol and opiate addicts and results in a significant reduction in craving ratings. The treatment showed that NAD can be used as a potential long-term therapy to help maintain sobriety through minimizing drug cravings and preventing relapse.

Why NAD+ IV Treatment Matters

NAD+ IV treatments are effective for use during recovery from alcohol, nicotine and opioids addictions. At the same time, NAD IV transfusions can help improve your:

The Food and Drug Administration (FDA) sees NAD IV as a treatment method with future potential and says that it is “inherently safe” at doses of 2g a day or less. It is also preferred because NAD IV offers a way to address benzodiazepine dependence. Overall, FDA considers NAD IV treatments as “Clearly the best current solution to the expanding problems of drug abuse (particularly heroin), prescription drug abuse, and post-acute withdrawal syndrome (PAWS).”

How At Home NAD+ IV Therapy Works

Here’s how it works and what you can expect when you receive IV NAD for addiction at home.

  1. At the initial consultation, our medical team determines your therapy depending on your drug history and your specific needs according to your drug addiction recovery treatment plan.
  2. The medical team then prepares the specifically tailored drug addiction recovery formula for you based on the latest scientific research and to optimize treatment results for you.
  3. The exact frequency of treatment—whether its daily or every other day—may vary from person to person and is determined at the initial consultation. Most treatment regimens last 10 days or more.
  4. The typical treatment is made up of 500mg of NAD+ together with 1 liter of saline solution.
  5. Each IV treatment session at your home delivers a set amount of NAD+.

Take the First Step towards Better Health with NAD Therapy

Take control of your health and address your biggest health concerns with NAD therapy. Consult with a trusted medical professional today to explore the potential benefits of NAD and find personalized solutions for your unique needs.

  • Convenience
  • Comfort
  • Privacy
  • Personalized care
  • Flexible scheduling

Transform your health with NAD therapy and experience the life-changing benefits of personalized treatment tailored to your unique needs.

NAD - Frequently Asked Questions

What is NAD?

NAD is a coenzyme that is naturally produced by the body and is essential for various physiological processes, including energy production and DNA repair. It is found in all living cells and plays a critical role in many of the body's metabolic processes. NAD is a dinucleotide, which means that it consists of two nucleotides joined together. It is made up of two molecules: nicotinamide and adenine, which are joined together by a phosphate group.

NAD is involved in a wide range of biological processes, including the metabolism of carbohydrates, proteins, and fats, and is essential for the proper functioning of the body's cells and tissues.

What can I expect during a NAD IV treatment?

Our nurse will arrive at your location of choice with all the equipment necessary for the appointment. They will then administer the IV into your arm and stay with you to monitor the treatment and answer any questions you may have.

Our NAD IV treatments generally last couple of hours per session. You can sit back, watch a movie or a favorite show, browse social media, or even work while the treatment is in progress.

What sets Drip Hydration apart from other NAD IV treatment providers?

Drip Hydration brings appointments directly to you whether you are at home, at a hotel, or at the office. We make getting at home NAD IV treatments easy and convenient, saving you the time and hassle of sitting in traffic or waiting in a clinic.

Is NAD right for me?

You don’t have to wait until you are experiencing a medical condition to enjoy the benefits of NAD IV therapy. NAD plays a role in hundreds of chemical functions throughout your body. This versatile treatment helps promote whole-body wellness and can help your body maintain optimal performance over time.

Is IV therapy FDA approved?

IV therapy in general is FDA approved. Our nurses are overseen by our Medical Director, Abe Malkin, and every nurse is registered and certified per state standards.

Is NAD safe?

NAD is considered a dietary supplement, not a drug. The FDA does not currently evaluate dietary supplements in their current regulations. However, NAD is well-tolerated, meaning that there are rarely side effects.

How long do IV treatments take?

Our IV NAD treatments take couple of hours to administer per session. The number of sessions vary by individual and will be determined during your initial consultation.

Does NAD help battle aging?

Some studies have suggested that NAD may have anti-aging effects by helping to support the production of enzymes that are involved in DNA repair and maintenance, which are essential for maintaining healthy cells and tissues. Additionally, NAD may support the production of enzymes that are involved in the body's natural detoxification processes, which can help to reduce the effects of oxidative stress and support healthy aging. 

Does NAD Improve metabolic function?

Some studies have suggested that NAD may support healthy metabolism by helping to regulate the body's energy production and utilization, and may also support the production of enzymes that are involved in various metabolic processes. Additionally, NAD may support the body's natural detoxification processes, which are important for maintaining overall health and wellness.

How often can I get an NAD treatment?

NAD IV treatments are most effective when used over time. You can get treatments several times per month unless you are otherwise advised during your initial consultation.

What can I expect to feel after a NAD IV drip?

Following a NAD IV drip, most patients feel more energetic, clearer-headed, and focused. Regular treatments may improve these effects over time.

Is there any downtime or recovery after a NAD drip?

Not at all! You can resume your normal activities immediately after your appointment. Where do you deliver NAD IV treatments? Drip Hydration delivers NAD IV treatments anywhere within our service areas, which you can find on our service area pages. That said, we recommend choosing a comfortable place for NAD treatments since this type of IV takes couple of hours per appointment.

How is IV NAD better than an oral NAD supplement?

IV NAD is delivered directly into your bloodstream, where it becomes available to your cells for immediate use. Because NAD bypasses the digestive and metabolic systems, you can expect a 100% absorption rate for maximum effect and minimal waste. Oral NAD supplements, on the other hand, must pass through your digestive system, where they are partly metabolized before your body has access to orally given NAD.

What is the difference between a NAD IV and a vitamin drip?

There are two main differences between a NAD IV and a Vitamin Drip: duration and ingredients. NAD IVs generally take couple of hours to administer per session while vitamin drips take 30 - 45 minutes. Our vitamin drips are specially blended to improve a variety of symptoms and ailments. Our NAD+ Boost treatments contains vitamins that can help make this IV more effective with longer-lasting effects.

Do I need any special supplies for my NAD IV appointment?

No, you do not need any special supplies. Our nurse will bring everything needed for the appointment.

Does NAD improve brain health and function?

NAD is believed to have potential benefits for brain health and function, although more research is needed to fully understand its effects. Some studies have suggested that NAD may have neuroprotective effects, meaning that it may help to protect the brain from damage and support healthy brain function. Additionally, NAD may support the production of neurotransmitters, which are chemicals that help to transmit signals between the brain's cells, and may help to improve cognitive function and memory.


[2] NIDA - Fentanyl.;

[1] The Drug Overdose Epidemic: Behind the Numbers;

[3] Sinha R - New findings on biological factors predicting addiction relapse vulnerability.;

[4] Menon J. - Relapse prevention.;

[5] Braidy N. - Sobriety and Satiety: Is NAD+ the Answer?;

[6] Miller M. - Early intervention of intravenous KB220IV--neuroadaptagen amino-acid therapy (NAAT) improves behavioral outcomes in a residential addiction treatment program: a pilot study.;

[7] Alexandrovich YG. - Rapid Elimination of Blood Alcohol Using Erythrocytes: Mathematical Modeling and In Vitro Study.;