Nicotinamide adenine dinucleotide (NAD) is a cofactor or coenzyme that occurs naturally in the body. It participates in a multitude of biological processes in the body, from the generation of adenosine triphosphate (ATP) in the brain to calcium signaling in the bones. Although scientists have identified many ways NAD assists biological processes in the body, they believe there are still dozens of other interactions yet to be discovered that further underscore its importance in the body.
Over time, however, natural NAD levels begin to fall, signaling the start of the aging process. Scientists believe that since NAD plays such a crucial role in so many biological processes in the body, its decline causes these processes to malfunction or slow down, leading to aging.
What is NAD+ therapy?
NAD+ therapy hinges on the idea that if a fall in NAD levels in the body triggers aging, replenishing these levels can slow down or even reverse the effects of aging.
During the treatment, a registered nurse practitioner administers an NAD+ solution via an intravenous drip. The drip delivers the vitamins to the bloodstream, increasing the amount of NAD in the body.
NAD+ therapy replenishes and stabilizes NAD levels in the body, enabling all related biological processes to continue normally. These effects make NAD+ therapy a promising anti-aging treatment that can slow down or, one day, even halt and reverse the effects of aging altogether.
NAD+ therapy benefits
Although NAD+ therapy cannot yet help us achieve immortality, it does have compelling age-defying benefits. Here are the top five benefits of NAD+ therapy.
1. NAD helps protect the brain during aging
NAD participates in multiple biological processes in the brain, including the production of ATP, the brain’s primary energy molecule. As the body ages, falling NAD levels expose the brain to age-related factors like chronic inflammation, oxidative stress, and impaired mitochondrial function.
NAD helps manage production of the PGC-1-alpha protein, which protects brain cells from these age-related factors. Oxidative stress is cellular damage resulting from an overabundance of free radicals, which are generated by various body processes. The brain uses 20% of the body’s oxygen supply, making brain cells particularly vulnerable to oxidative stress.
Damage due to these age-related issues impairs the brain’s plasticity, or ability to adapt to changing environments. They also negatively impact neuronal stress resistance, which affects cellular messaging. Messages may be sent at higher rates than normal or fail to send altogether.
These factors may cause age-related neurodegenerative disorders like Alzheimer’s disease and Parkinson’s disease. Replenishing NAD levels via regular IV therapy sessions give the brain the tools it needs to combat age-related neurodegeneration.
2. NAD helps repair DNA
Scientists believe that a fall in NAD levels causes age-related DNA degeneration, impairing mitochondrial-led gene expression and protein synthesis. For example, one study found that cancer cell growth (a result of faulty gene expression) was correlated to a decline in cellular NAD levels.
However, increasing NAD supply to such cells slowed down or, in some cases, reversed the growth of the cancer cells. Therefore, taking regular IV infusions of NAD+ can help support mitochondrial-led gene expression, repair faulty DNA, and prevent the formation of disease-causing proteins. Regular sessions help brain cells retain plasticity and increase signaling for cell renewal and regeneration. This may improve cognitive functions like learning, concentration, and reaction times.
3. NAD supports addiction recovery
Addiction impacts multiple functions in the brain, including the regulation of dopamine, circadian cycles, and satiety. Scientists have discovered that NAD plays a crucial role in all these processes and that increasing NAD levels can counter the effects of addiction. For example, increased levels of NAD through IV therapy heighten sirtuins (SIRT1 and SIRT2) levels, which in turn modulate behavioral responses to morphine and cocaine.
NAD also aids recovery from substance abuse disorder by:
- Reducing withdrawal effects, which helps prevent relapse motivated by an attempt to relieve uncomfortable or painful detox symptoms
- Lessens pain and curbs cravings associated with withdrawal, helping to curb relapse.
- Helps the body naturally generate energy, combating detox-related fatigue. This also helps prevent caffeine or sugar crashes resulting from attempts to boost energy with sugar, caffeine, or other substances.
- Helps flush drugs from the body
Individuals who use NAD alongside standard drug rehab treatments may experience a reduction in acute withdrawal symptoms from alcohol or opiates such as:
When used to aid addiction recovery, NAD therapy generally consists of multiple sessions over a period of time. The duration and frequency of NAD treatments may vary depending on the substance(s) involved, the severity of the addiction, and other health factors.
Other ways NAD IV therapy can combat addiction include restoring normal dopamine response levels, regulating addiction-induced anxiety, and restoring energy metabolism in the brain to ward off cravings.
4. NAD may improve mood disorders
Mood disorders like anxiety and depression are linked to a neurochemical imbalance in the brain. When hormones like dopamine, oxytocin, and melatonin are out of balance, the result is a mood disorder.
NAD plays a crucial role in the synthesis of these hormones and other mood-related biological processes, and scientists believe low NAD levels might be one of the reasons they fall out of balance. NAD IV therapy replenishes NAD levels in the brain, regularizing hormone synthesis, and improving mood and mental clarity.
5. NAD can help boost energy levels
One of NAD’s primary functions in the body is the production of adenosine triphosphate (ATP), an energy molecule that powers most cellular functions. NAD+ IV infusion increases the amount of NAD in the body, which triggers the production of more ATP. When the cells have enough energy to operate at optimal levels, the overall effect is more energy at a body level, translating into improved athletic performance, increased endurance, and heightened mental clarity. Low ATP levels have been linked to chronic fatigue syndrome.
NAD has been explored as a possible treatment for chronic fatigue syndrome due to its essential roles in energy production. Research is still ongoing to determine the various ways NAD aids energy production, however there are some additional theories regarding NAD’s benefits, including:
- NADH is believed to help in neurotransmitter creation, specifically those related to cognitive function and mood.
- NAD helps restore mitochondrial function to help reduce fatigue
- NAD can help stimulate brain function, which appears to help relieve cognitive dysfunction symptoms linked to chronic fatigue syndrome
NAD supplementation increases metabolism as well, which has been linked to weight loss. It should be noted that research is still ongoing regarding NAD as a weight loss treatment. Combating the drop of NAD levels as you age with IV therapy treatments can help prevent decline in metabolic function.
Does NAD therapy have any side effects?
So far, research indicates that NAD is a safe treatment with few side effects. However, because studies of NAD therapy are relatively new, the long-term side effects are unknown. Currently, the mild-to-moderate side effects of NAD therapy reported by study participants include:
- Abdominal pain
- Diarrhea, indigestion, and nausea
Administering treatments with IV therapy also has some risks, however these are significantly mitigated when seeking treatment from a licensed, trained healthcare professional following hygiene protocols and safety practices.
- Infection at injection site
- Air embolism
- Vein damage
Your NAD provider should conduct a health screening before beginning treatments to make sure NAD therapy is the best choice for you. You should also check the lab providing the therapies. You should look for labs that are certified that operate according to U.S. Food and Drug Administration (FDA) operating standards.
Enjoy The Benefits of NAD+ IV Therapy At Home
The benefits listed above represent but the tip of the iceberg when it comes to the potential benefits of NAD IV therapy. Scientists are still unraveling the complex ways NAD influences biological processes in the body, which might lead to a better understanding of just how far-reaching its benefits are.
Drip Hydration is a private NAD+ IV therapy provider that offers convenient in-home treatments administered by a licensed nurse practitioner. If you would like to experience the benefits of NAD+ for yourself, schedule an in-home or in-office NAD+ IV therapy session today by giving us a call or clicking the link below!