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How Often Should You Take NAD and What’s the Right Dosage?

The amount of nicotinamide adenine dinucleotide (NAD) a person takes depends on their health, their goals, and their tolerance. 1While there isn’t a set dosage or frequency for NAD precursors like nicotinamide riboside or nicotinamide mononucleotide, some people may choose to take 100–500 mg of these orally daily but the most often prescribed dose is 500 milligrams though an infusion. It’s crucial to speak with a medical expert who can advise you on the ideal dosage and frequency based on your unique requirements.

NAD's Role in Your Metabolism

NAD works on mitochondria and increases the length of telomeres, which are the protective caps located at the ends of chromosomes that become shorter as the body ages. NAD increases the activity of SIRT1 and PARP 1 proteins, which are linked with a slower rate of aging and influencing DNA repair respectively. – source

Nicotinamide Adenine Dinucleotide, or NAD, is a coenzyme that naturally occurs in our bodies and plays a vital role in generating energy. 2

As we grow older, our NAD levels diminish and further deteriorate because of:3

  • stress
  • lack of sleep
  • poor eating habits
  • consumption of drugs
  • consumption of alcohol

NAD for Mental Clarity

NAD is vital, especially to improve your:

  • mental clarity
  • focus
  • concentration
  • alertness

This is the main reason why college students tend to gravitate towards NAD supplements or IV treatments so that they can do well in school.

NAD can also help treat:

mental clarity nad, woman meditating on a cliff

With all the benefits that NAD brings, it’s not surprising why its usage has been on an upward incline the past few years. It has certainly grown in popularity, especially since more and more people are getting to know its benefits.

Key Takeaway: NAD is an important component in improving mental clarity, attention, concentration, and alertness, making it popular among students pursuing academic achievement. NAD is also being researched for its possible involvement in the treatment of Alzheimer’s disease, dementia, and the reversal of alcohol-induced liver damage. It is also considered to help reverse the effects of aging and improve athletic performance. The increased understanding of these possible advantages has resulted in an increase in NAD consumption in recent years.

The Right NAD Dosage

nad dosage measurement level

When it comes to NAD dosage, it is best to talk to a health professional so that they can get a full analysis of your current state of health and recommend the best NAD dosage for optimum effects. It is not advisable to self-medicate in any circumstances. Self-medicating can lead to the consumption of incorrect doses that can’t be tolerated by your body, bringing detrimental effects.

The NAD Dosage that you have to take depends on your health condition and the effects that you want to come out of it.

Determining Your NAD Dosage

The typically prescribed dosage is between 5 milligrams to 10 milligrams per day. However, your ideal NAD dosage may be influenced by several factors.

NAD levels naturally decline over time due to age, environment, and stress. A consistent lack of sleep and poor diet can also deplete NAD levels. Genetics may also play a role in NAD deficiency.

Older individuals or those with genetic factors may require a higher dosage or more frequent applications of NAD to help restore and maintain optimal levels. Younger individuals may only require treatments once every few months.

Additionally, the type of NAD you choose can impact the dosage and treatment frequency.

IV infusions: Contains 500mg of NAD in 500 ml of saline solution, typically administered multiple times over the course of several weeks.
Injections: A 500 mg or 1000mg vial is self-administered using a subcutaneous injection over a set period of time.
Nasal sprays: Contains 30 mg/spray in a 300 mg/ml bottle, typically administered once per day.
Oral supplements: Oral medications that may be taken once or twice daily. The exact amount of NAD in a supplement varies by manufacturer, but it is important to remember that this option offers the least bioavailability as supplements need to pass through your digestive system.

Your doctor will evaluate your goals and current health to help determine an ideal dosage and treatment frequency.

How Often Should You Take NAD?

It depends on your health goals. IV treatments typically take place several times per week over the course of several weeks.

Following the initial course of treatment, you can get booster shots or follow-up infusions every few months to maintain results.

Oral NAD, on the other hand, may be taken once or twice daily depending on manufacturer recommendations.

Pills organizer full of pills and a phone with reminder on

People with chronic or more intensive needs may receive IV treatments several times per year. People who are receiving treatment to maintain optimal health may only need one or two infusions.

NAD is most effective when used regularly over time. Treatments help reverse existing damage to your body and slow the progression of additional damage and age-related changes.

One study on mice demonstrated that regular NAD supplementation offered therapeutic results for weight loss and management. Another study determined that regular use of NAD helped patients manage addiction by helping restore overall health and wellness.

NAD supplements are generally safe to take and come with few side effects, even at higher doses. However, if your supplement contains other ingredients such as vitamins or minerals, it may be possible to consume too much of certain components.

Key Takeaway: Consultation with a healthcare practitioner is essential for choosing the correct NAD dose since they can examine your health and prescribe the best dosage for you. Self-medication may result in the consumption of improper dosages, which may have negative consequences. Your NAD dose will be determined by your overall health and your individual health goals. The normal prescription dose ranges from 5 milligrams to 10 milligrams per day.

Safety Considerations

Ensuring your safety when considering NAD supplements is paramount, as an excess of beneficial substances can occasionally yield adverse consequences.

Some individuals may encounter uncomfortable side effects, such as gastrointestinal issues that manifest as nausea, diarrhea, or abdominal cramping. It is worth noting that while these side effects are typically not severe, they can be bothersome.

NAD supplements may not interact favorably with certain medications. Particularly, if you are currently prescribed medications that affect or are metabolized by your liver, introducing NAD into your regimen may interfere with the efficacy of these drugs.

If you are presently taking any medications for health-related issues, engaging in a comprehensive discussion with your healthcare provider is strongly advisable before embarking on NAD supplementation.

As you consider incorporating NAD supplements into your routine, monitoring your body’s responses meticulously is essential. Pay careful attention to any fluctuations in your energy levels and assess whether your health goals show improvement.

Maximizing the Benefits of NAD Supplementation

NAD, or Nicotinamide Adenine Dinucleotide, is a critical coenzyme involved in various cellular processes, including energy production and DNA repair. NAD levels tend to decline with age, and this decrease has been linked to various age-related diseases. Supplementation has gained popularity as a potential strategy to boost NAD levels and support overall health.

To maximize the benefits of regular supplement use, adopting a proper NAD dosage with a balanced diet and lifestyle, stress reduction, healthy sleep patterns, regular physical activity, and optimizing cellular health is essential.

Adopting a Balanced Diet and Lifestyle

A well-rounded diet rich in essential nutrients is crucial for optimal NAD levels. Foods like dairy products, lean meats, fish, and nuts contain precursors to NAD synthesis, such as tryptophan and niacin.

Additionally, avoiding excessive alcohol consumption and limiting the intake of sugary and processed foods can help maintain stable NAD levels. Adopting a balanced lifestyle, including managing body weight, avoiding smoking, and moderating caffeine intake, can further support NAD metabolism.

Reducing Stressors and Promoting Healthy Sleep

Chronic stress and poor sleep quality can deplete NAD levels. Practicing stress management techniques like meditation, yoga, or mindfulness can help reduce the impact of stress on NAD. Prioritizing healthy sleep patterns, including consistent sleep schedules and creating a conducive sleep environment, can aid in NAD restoration. Adequate sleep allows the body to repair and regenerate, including the synthesis of NAD.

Engaging in Regular Physical Activity

Exercise has numerous benefits, including its potential to boost NAD levels. Regular physical activity stimulates NAD production and enhances mitochondrial function, improving overall cellular energy production. Combining aerobic and strength-training exercises can maximize these effects and contribute to better NAD utilization.

Optimizing Cellular Health

Cellular health is fundamental for NAD metabolism. Intermittent fasting, which involves cycles of eating and fasting, has been shown to stimulate NAD production and help improve cellular health.

Additionally, various supplements, such as resveratrol and quercetin, may support NAD supplementation frequency and increase NAD levels and cellular function. Consultation with a healthcare professional before starting any supplement regimen is recommended.

When is IV the best option?

Contact our offices and our team of medical professionals led by founders Dr. Abe Malkin and Dr. Neal Kumar, will answer your queries.

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Oral vs IV NAD

If you’re considering NAD but can’t decide between oral and IV infusions, here are some pros and cons to consider.


  • Patients can receive the maximum amount of NAD since treatments do not have to pass through the digestive system, where some components are lost due to the digestive process
  • In-home treatments are convenient and administered by a registered nurse
  • IV infusions contain additional vitamins and hydration for additional health benefits and long-lasting effects


  • Most patients will need multiple infusion sessions per week during the course of treatment
  • Not ideal for individuals with an aversion to needles


  • Highly convenient, as supplements can be obtained over-the-counter or online
  • Easy to take once or twice daily alongside other regular medications
  • Affordable and portable, which is ideal for regular travelers


  • Not ideal for individuals who have difficulty taking oral supplements
  • Patients do not receive the full dose of NAD, as some is lost during the digestive process
  • Some patients may find it challenging to remember to take their pills on a daily basis

Regardless of whether you choose oral or IV NAD, it’s important to talk to your healthcare provider before starting treatment to make sure treatment is right for you.

Key Takeaway: IV NAD allows optimal absorption and includes extra vitamins but requires regular sessions and isn’t suitable for those uncomfortable with needles. Oral NAD is easily accessible and convenient for travelers but might not be ideal for those struggling with taking supplements and has less absorption due to digestion. Consult a healthcare provider before starting any treatment.

Contact Drip Hydration

To get the best recommendation for NAD dosage, don’t hesitate to contact Drip Hydration today! Take the guesswork out of self-medication and talk to our highly qualified professional clinicians to get the best results from NAD treatments.

Take the First Step towards Better Health with NAD Therapy

Take control of your health and address your biggest health concerns with NAD therapy. Consult with a trusted medical professional today to explore the potential benefits of NAD and find personalized solutions for your unique needs.

  • Convenience
  • Comfort
  • Privacy
  • Personalized care
  • Flexible scheduling

Transform your health with NAD therapy and experience the life-changing benefits of personalized treatment tailored to your unique needs.

NAD - Frequently Asked Questions

What is NAD?

NAD is a coenzyme that is naturally produced by the body and is essential for various physiological processes, including energy production and DNA repair. It is found in all living cells and plays a critical role in many of the body's metabolic processes. NAD is a dinucleotide, which means that it consists of two nucleotides joined together. It is made up of two molecules: nicotinamide and adenine, which are joined together by a phosphate group.

NAD is involved in a wide range of biological processes, including the metabolism of carbohydrates, proteins, and fats, and is essential for the proper functioning of the body's cells and tissues.

What can I expect during a NAD IV treatment?

Our nurse will arrive at your location of choice with all the equipment necessary for the appointment. They will then administer the IV into your arm and stay with you to monitor the treatment and answer any questions you may have.

Our NAD IV treatments generally last couple of hours per session. You can sit back, watch a movie or a favorite show, browse social media, or even work while the treatment is in progress.

What sets Drip Hydration apart from other NAD IV treatment providers?

Drip Hydration brings appointments directly to you whether you are at home, at a hotel, or at the office. We make getting at home NAD IV treatments easy and convenient, saving you the time and hassle of sitting in traffic or waiting in a clinic.

Is NAD right for me?

You don’t have to wait until you are experiencing a medical condition to enjoy the benefits of NAD IV therapy. NAD plays a role in hundreds of chemical functions throughout your body. This versatile treatment helps promote whole-body wellness and can help your body maintain optimal performance over time.

Is IV therapy FDA approved?

IV therapy in general is FDA approved. Our nurses are overseen by our Medical Director, Abe Malkin, and every nurse is registered and certified per state standards.

Is NAD safe?

NAD is considered a dietary supplement, not a drug. The FDA does not currently evaluate dietary supplements in their current regulations. However, NAD is well-tolerated, meaning that there are rarely side effects.

How long do IV treatments take?

Our IV NAD treatments take couple of hours to administer per session. The number of sessions vary by individual and will be determined during your initial consultation.

Does NAD help battle aging?

Some studies have suggested that NAD may have anti-aging effects by helping to support the production of enzymes that are involved in DNA repair and maintenance, which are essential for maintaining healthy cells and tissues. Additionally, NAD may support the production of enzymes that are involved in the body's natural detoxification processes, which can help to reduce the effects of oxidative stress and support healthy aging. 

Does NAD Improve metabolic function?

Some studies have suggested that NAD may support healthy metabolism by helping to regulate the body's energy production and utilization, and may also support the production of enzymes that are involved in various metabolic processes. Additionally, NAD may support the body's natural detoxification processes, which are important for maintaining overall health and wellness.

How often can I get an NAD treatment?

NAD IV treatments are most effective when used over time. You can get treatments several times per month unless you are otherwise advised during your initial consultation.

What can I expect to feel after a NAD IV drip?

Following a NAD IV drip, most patients feel more energetic, clearer-headed, and focused. Regular treatments may improve these effects over time.

Is there any downtime or recovery after a NAD drip?

Not at all! You can resume your normal activities immediately after your appointment. Where do you deliver NAD IV treatments? Drip Hydration delivers NAD IV treatments anywhere within our service areas, which you can find on our service area pages. That said, we recommend choosing a comfortable place for NAD treatments since this type of IV couple of hours per appointment.

How is IV NAD better than an oral NAD supplement?

IV NAD is delivered directly into your bloodstream, where it becomes available to your cells for immediate use. Because NAD bypasses the digestive and metabolic systems, you can expect a 100% absorption rate for maximum effect and minimal waste. Oral NAD supplements, on the other hand, must pass through your digestive system, where they are partly metabolized before your body has access to orally given NAD.

What is the difference between a NAD IV and a vitamin drip?

There are two main differences between a NAD IV and a Vitamin Drip: duration and ingredients. NAD IVs generally take couple of hours to administer per session while vitamin drips take 30 - 45 minutes. Our vitamin drips are specially blended to improve a variety of symptoms and ailments. Our NAD+ Boost treatments contains vitamins that can help make this IV more effective with longer-lasting effects.

Do I need any special supplies for my NAD IV appointment?

No, you do not need any special supplies. Our nurse will bring everything needed for the appointment.

Does NAD improve brain health and function?

NAD is believed to have potential benefits for brain health and function, although more research is needed to fully understand its effects. Some studies have suggested that NAD may have neuroprotective effects, meaning that it may help to protect the brain from damage and support healthy brain function. Additionally, NAD may support the production of neurotransmitters, which are chemicals that help to transmit signals between the brain's cells, and may help to improve cognitive function and memory.

NAD Injection Therapy

What are the benefits of NAD Injection Therapy?

NAD injection therapy is believed to have several potential benefits, including improving energy levels, supporting cognitive function, reducing inflammation, and supporting the body's natural detoxification processes. Additionally, NAD injection therapy is often used in combination with other treatments, such as IV vitamin therapy, to support the body's natural recovery processes and improve overall health and wellness.

What is the difference between NAD injection vs NAD IV therapy?

The main difference between NAD injection and NAD IV therapy is the method of delivery. NAD injection involves injecting NAD directly into the bloodstream using a syringe, while NAD IV therapy involves infusing NAD into the bloodstream through a small tube that is inserted into a vein.

What is the difference between NAD injections and NAD supplements?

The main difference between NAD injections and NAD supplements is the method of delivery. NAD injections involve injecting NAD directly into the bloodstream using a syringe, while NAD supplements are taken orally in the form of pills or capsules.

How to best self-administer a NAD injection?

When administering the injection, it is important to use a clean, sterile needle and syringe, and to inject the NAD into a vein using a slow, steady motion. It is also important to properly dispose of the used needles and syringes to avoid the risk of injury or infection. It is also important to carefully follow the instructions provided by the healthcare professional and the manufacturer of the NAD injection, including proper storage and handling of the injection and any necessary preparation steps.

NAD+ Nasal Spray

What are the benefits of NAD+ nasal spray?

NAD+ nasal spray is believed to have several potential benefits, including improving energy levels, supporting cognitive function, reducing inflammation, and supporting the body's natural detoxification processes.

What is the difference between NAD injection and NAD+ nasal spray?

The main difference between NAD injection and NAD+ nasal spray is the method of delivery. NAD injection involves injecting NAD directly into the bloodstream using a syringe, while NAD+ nasal spray involves delivering NAD directly into the bloodstream through the nose.

What is the difference between NAD+ nasal spray and NAD supplements?

The primary distinction between NAD+ nasal spray and NAD supplements is the route of administration. NAD+ nasal spray delivers NAD directly into the bloodstream via the nose, whereas NAD supplements are taken orally as tablets or capsules.

How often can I use the NAD+ nasal spray?

The frequency of NAD+ nasal spray use will depend on the specific product and the individual's needs and preferences. It is important to consult with a healthcare professional to determine the appropriate frequency of NAD+ nasal spray use, as well as any potential risks or side effects. In general, NAD+ nasal spray can be used daily or as needed, depending on the individual's goals and needs. It is also important to carefully follow the instructions provided by the healthcare professional and the manufacturer of the NAD+ nasal spray, including any recommended dosing guidelines and precautions.

What can I expect to feel after using the NAD+ nasal spray?

The effects of NAD+ nasal spray may vary depending on the individual and their unique physiology and health needs. In general, people may experience improved energy levels, cognitive function, and overall health and wellness after using NAD+ nasal spray. Additionally, NAD+ nasal spray may help to support the body's natural recovery processes and reduce the symptoms of conditions such as chronic fatigue syndrome, fibromyalgia, and addiction.


[1] WebMD - Nadh - Uses, Side Effects, and More;

[2] Braidy N. - Role of Nicotinamide Adenine Dinucleotide and Related Precursors as Therapeutic Targets for Age-Related Degenerative Diseases: Rationale, Biochemistry, Pharmacokinetics, and Outcomes.;

[3] Chini CCS. - NAD and the aging process: Role in life, death and everything in between.;