Crop female pharmacist with pile of white pills on palm

The Safety And Effectiveness of Glutathione Supplements

Crop female pharmacist with pile of white pills on palm

Are you considering glutathione supplements to improve your health and well-being? If so, you’re not alone. Glutathione supplements have become increasingly popular due to their potential health benefits.

We invite you to learn more about glutathione IV therapy and determine if it is the right treatment to help you reach your health goals.

What are the benefits of glutathione supplement products?

Glutathione is an antioxidant found naturally in the body that helps to protect cells from damage and maintain overall health. It can also be taken as a supplement to boost the body’s natural production of glutathione.

Medicines on the Table

Supplementing with glutathione can help to boost levels of this powerful antioxidant, potentially offering a range of health benefits.

Glutathione helps to protect the body from oxidative stress caused by free radicals, which can damage cells and tissues over time. As a result, supplementing with glutathione may be able to help slow down the aging process.

Glutathione supplementation has also been studied for its potential to improve the health of people with certain chronic illnesses, such as cystic fibrosis and Parkinson’s disease.1 Supplementation can help to reduce inflammation and improve symptoms of both conditions.

In addition, glutathione supplementation can improve liver health.2 Glutathione helps to neutralize toxins in the liver, reducing the strain on this vital organ. Supplementation has been shown to reduce fat and cholesterol levels in the liver, which can help prevent serious liver diseases like cirrhosis.

Finally, glutathione supplementation can improve immune system health. Low glutathione levels have been linked to increased susceptibility to infection and inflammation.3 Supplementing with glutathione may help boost immunity and reduce the risk of infection.

Are glutathione supplements safe?

Overall, it appears that glutathione supplements are safe and effective when used correctly according to guidelines set forth by your physician.

Glutathione is generally well tolerated, with few side effects reported. Side effects vary depending on the type of supplement used, which we’ll discuss below.

Furthermore, different administration forms have varying degrees of effectiveness, so discussing your needs with your healthcare provider is important before starting any supplementation regimen.

Oral supplements

Oral glutathione supplements typically come in capsule, tablet, powder, and liquid forms. They are taken at intervals as directed by the manufacturer.

For these types of supplements, it is important to carefully review the ingredient’s label to determine potency and check for contaminants such as heavy metals.

pill box with different types of pills

Common side effects are typically mild and include:

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal discomfort

Oral supplements may not be as effective at boosting glutathione levels as IV or Im due to absorption issues; however, they are generally considered safe when taken at the recommended dosage.

Intravenous and Intramuscular administration

Glutathione IV therapy is a method of administering the supplement directly into the bloodstream to boost levels quickly and effectively. Treatments typically take less than an hour.

Intramuscular administration comes in the form of a single shot that is generally administered into your arm. This procedure only takes a couple of minutes.

hanging normal Saline IV bag with green plants in the background

Both IV and IM administration bypass the gastrointestinal system, meaning more supplements can reach the cells for maximum benefit. Glutathione can then circulate throughout the body immediately, providing antioxidants and other health benefits.

Common side effects of IV and IM glutathione may include:

  • Headaches
  • Nausea
  • Vomiting
  • Dizziness

More serious side effects may include allergic reactions, anaphylaxis, and low blood pressure.

It is safest to only seek glutathione IV therapy and IM injections from licensed and trained healthcare professionals. A reliable doctor will conduct a health screening before beginning treatment to ensure glutathione is the right choice for you.

Final thoughts

Overall, there is promising evidence that glutathione supplementation can offer a range of health benefits. While more research is needed to further evaluate the efficacy of supplementing with glutathione, it may be an effective way to boost levels of this powerful antioxidant and improve overall health.

Whether you take it intravenously, through injections, or orally, it’s important to consult a licensed healthcare professional first to determine the best action for your particular situation. While glutathione may offer benefits, it’s important to consider all potential risks and use it under the guidance of a qualified medical practitioner.

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Glutathione - Frequently Asked Questions

What is glutathione?

Glycine, cysteine, and glutamic acid are the building blocks for the compound glutathione. It is created by the liver and is used by several bodily functions. Glutathione helps with the production of chemicals and proteins required by the body, as well as immune system activity.

What are the benefits of taking glutathione?

Taking glutathione has many benefits including:

  • Reducing oxidative stress
  • Reducing cell damage in alcoholic and nonalcoholic liver disease
  • Improves insulin resistance in older people
  • Increase mobility for people with peripheral artery disease
  • Reduces symptoms of Parkinson’s disease
  • Might help fight autoimmune diseases
  • Might reduce oxidative damage in children with autism
  • Might reduce the impact of uncontrolled diabetes
  • Might reduce respiratory disease symptoms
  • Might improve psoriasis

Glutathione IV Therapy vs supplements

Glutathione supplementation has been related to digestive problems, such as bloating or stomach cramps. Intravenous glutathione provides the antioxidant directly to your cells by totally avoiding the digestive system.

Does glutathione help reduce oxidative stress?

According to one research, glutathione either increases or decreases the body's immune response, which helps alleviate oxidative stress. Diseases with an autoimmune component damage particular cells' mitochondria. By scavenging free radicals, glutathione protects the mitochondria of the cell.


[1] Otto M. - The Use of Intravenous Glutathione for Symptom Management of Parkinson's Disease: A Case Report.;

[2] Sacco R. - Glutathione in the treatment of liver diseases: insights from clinical practice.;

[3] Dröge W. - Glutathione and immune function.;