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NAD Biology: Unlocking Its Potential for Health & Wellness

Woman Wearing Black Bra and White Tank Top Raising Both Hands on Top

Understanding how the body operates is a critical aspect of staying healthy. One component particularly influential to our health and wellness is the coenzyme nicotinamide adenine dinucleotide or NAD. NAD is one of the essential parts of all the cells in our body and impacts nearly everything we do, including the aging process. Recent research has shown the benefits of NAD and how supplementing NAD levels can improve overall health and wellness even in old age.

Here we will talk about NAD, the biology of the substance, what it does, how it impacts the body, and how supplementing our natural NAD level can improve metabolic health, brain health, and athletic performance.

NAD Biology 101

NAD is a naturally occurring coenzyme, the result of the synthesis between specific amino acids, the building blocks of all life.1 NAD’s primary purpose is to help break down food into usable cellular energy and transfer that energy between cells to function normally, including cellular reproduction, DNA repair, metabolic function, immune response, brain cell response, and much more.2

Essentially, NAD takes the energy to the cells in exchange for oxygen. The oxygenated form of NAD, NAD+, is then metabolized in the bloodstream and broken down into remnants.

When enough NAD is present, cells can function normally, the body can repair itself efficiently, the metabolism is healthy, and overall performance improves. The problem is that as we age, the natural production of NAD decreases. Studies show that lack of NAD is directly related to the onset of age-related diseases such as diabetes and macular degeneration.

NAD and Aging

One of the most dynamic aspects of NAD is its effect on the aging process. Because NAD is vital to transferring energy between cells and DNA repair, this coenzyme is one of the key factors determining how well our body heals itself and how well our different organs function. For example, skin cells’ elasticity makes us look young and wrinkle-free.

woman looking at the mirror taking care of her skin

Our immune response and the ability of the body to repair the damage allow us to recover from injuries.

Even things like inflammation, the amount of cartilage between our joints, and other factors are all impacted by NAD. The problem is that the body starts to produce less and less NAD over time, about half as much from the age of adulthood throughout a person’s life. This decline makes us heal from injury slower, makes our skin start to sag and wrinkle, and can lead to age-related issues like arthritis and diabetes.

NAD and Cognitive Function

NAD impacts brain cells just like other parts of the body. With enough NAD, we can focus; our minds are sharp, recall information more quickly, and retain knowledge for longer. Without NAD, the brain starts to slow down, the memory becomes strained, and mental focus wanes.

MRI scan of a brain

Current research suggests that supplementing your NAD levels can improve cognitive function, including focus and memory, and reduce the risk of diseases like Alzheimer’s.3

NAD and Athletic Performance

Not only does NAD help fight off fatigue and promote higher energy levels, but it can also help improve metabolism, which can help keep weight off and enhance muscle growth.

The anti-inflammatory and healing properties of NAD can promote better movement of the joints and less potential for injury, and reduce recovery time between injuries.

man swimming in a pool

NAD could eventually allow athletes to perform better for longer, leading to longer careers for many sports and fewer injuries while active. Many athletes already see the advantages of regular supplementation to restore NAD reserves to healthy levels.

Potential Side Effects and Precautions

Though research is still early, results show no significant risk for severe side effects from NAD supplements. Some patients receiving injectable NAD may experience an allergic reaction at the injection site, headaches, mild brain fog, nausea, and cramping.

woman with her hands on her face on a black background with random white lines surrounding her

Before taking any NAD supplement, you must talk with your doctor about any other medications you are on and any symptoms you experience when first taking it. Taking too much may result in addiction and complications with the body’s natural production of needed substances.

It’s a good idea to talk with your doctor about NAD, what NAD therapy would look like for you, any lifestyle or health factors that may be an issue, and what the suitable form of NAD supplement is for your situation.

Final thoughts

NAD is a vital component in the overall wellness of our bodies. From anti-aging to disease prevention, improving cognitive and athletic performance, and boosting metabolic rate and function, the benefits of enhancing the amount of NAD in our bodies seem nearly endless.

Research is ongoing, but early results suggest that NAD has significant potential to help reverse aging and recover injuries. As always, talk with your doctor about what is appropriate for you and see how NAD can improve your health and wellness.

NAD IV Therapy in

Our NAD IV comes with a unique blend of vitamins to supercharge the effectiveness of NAD+, all done in the comfort of your own home, hotel or office. Our medical proffesionals come to your location in the % area, and administers the NAD+ infusion.

NAD - Frequently Asked Questions

What is NAD?

NAD is a coenzyme that is naturally produced by the body and is essential for various physiological processes, including energy production and DNA repair. It is found in all living cells and plays a critical role in many of the body's metabolic processes. NAD is a dinucleotide, which means that it consists of two nucleotides joined together. It is made up of two molecules: nicotinamide and adenine, which are joined together by a phosphate group.

NAD is involved in a wide range of biological processes, including the metabolism of carbohydrates, proteins, and fats, and is essential for the proper functioning of the body's cells and tissues.

What can I expect during a NAD IV treatment?

Our nurse will arrive at your location of choice with all the equipment necessary for the appointment. They will then administer the IV into your arm and stay with you to monitor the treatment and answer any questions you may have.

Our NAD IV treatments generally last 3 - 4 hours per session. You can sit back, watch a movie or a favorite show, browse social media, or even work while the treatment is in progress.

What sets Drip Hydration apart from other NAD IV treatment providers?

Drip Hydration brings appointments directly to you whether you are at home, at a hotel, or at the office. We make getting at home NAD IV treatments easy and convenient, saving you the time and hassle of sitting in traffic or waiting in a clinic.

Is NAD right for me?

You don’t have to wait until you are experiencing a medical condition to enjoy the benefits of NAD IV therapy. NAD plays a role in hundreds of chemical functions throughout your body. This versatile treatment helps promote whole-body wellness and can help your body maintain optimal performance over time.

Is IV therapy FDA approved?

IV therapy in general is FDA approved. Our nurses are overseen by our Medical Director, Abe Malkin, and every nurse is registered and certified per state standards.

Is NAD safe?

NAD is considered a dietary supplement, not a drug. The FDA does not currently evaluate dietary supplements in their current regulations. However, NAD is well-tolerated, meaning that there are rarely side effects.

How long do IV treatments take?

Our IV NAD treatments take between 3 - 4 hours to administer per session. The number of sessions vary by individual and will be determined during your initial consultation.

Does NAD help battle aging?

Some studies have suggested that NAD may have anti-aging effects by helping to support the production of enzymes that are involved in DNA repair and maintenance, which are essential for maintaining healthy cells and tissues. Additionally, NAD may support the production of enzymes that are involved in the body's natural detoxification processes, which can help to reduce the effects of oxidative stress and support healthy aging. 

Does NAD Improve metabolic function?

Some studies have suggested that NAD may support healthy metabolism by helping to regulate the body's energy production and utilization, and may also support the production of enzymes that are involved in various metabolic processes. Additionally, NAD may support the body's natural detoxification processes, which are important for maintaining overall health and wellness.

How often can I get an NAD treatment?

NAD IV treatments are most effective when used over time. You can get treatments several times per month unless you are otherwise advised during your initial consultation.

What can I expect to feel after a NAD IV drip?

Following a NAD IV drip, most patients feel more energetic, clearer-headed, and focused. Regular treatments may improve these effects over time.

Is there any downtime or recovery after a NAD drip?

Not at all! You can resume your normal activities immediately after your appointment. Where do you deliver NAD IV treatments? Drip Hydration delivers NAD IV treatments anywhere within our service areas, which you can find on our service area pages. That said, we recommend choosing a comfortable place for NAD treatments since this type of IV takes 3 - 4 hours per appointment.

How is IV NAD better than an oral NAD supplement?

IV NAD is delivered directly into your bloodstream, where it becomes available to your cells for immediate use. Because NAD bypasses the digestive and metabolic systems, you can expect a 100% absorption rate for maximum effect and minimal waste. Oral NAD supplements, on the other hand, must pass through your digestive system, where they are partly metabolized before your body has access to orally given NAD.

What is the difference between a NAD IV and a vitamin drip?

There are two main differences between a NAD IV and a Vitamin Drip: duration and ingredients. NAD IVs generally take 3 - 4 hours to administer per session while vitamin drips take 30 - 45 minutes. Our vitamin drips are specially blended to improve a variety of symptoms and ailments. Our NAD+ Boost treatments contains vitamins that can help make this IV more effective with longer-lasting effects.

Do I need any special supplies for my NAD IV appointment?

No, you do not need any special supplies. Our nurse will bring everything needed for the appointment.

Does NAD improve brain health and function?

NAD is believed to have potential benefits for brain health and function, although more research is needed to fully understand its effects. Some studies have suggested that NAD may have neuroprotective effects, meaning that it may help to protect the brain from damage and support healthy brain function. Additionally, NAD may support the production of neurotransmitters, which are chemicals that help to transmit signals between the brain's cells, and may help to improve cognitive function and memory.

NAD Injection Therapy

What are the benefits of NAD Injection Therapy?

NAD injection therapy is believed to have several potential benefits, including improving energy levels, supporting cognitive function, reducing inflammation, and supporting the body's natural detoxification processes. Additionally, NAD injection therapy is often used in combination with other treatments, such as IV vitamin therapy, to support the body's natural recovery processes and improve overall health and wellness.

What is the difference between NAD injection vs NAD IV therapy?

The main difference between NAD injection and NAD IV therapy is the method of delivery. NAD injection involves injecting NAD directly into the bloodstream using a syringe, while NAD IV therapy involves infusing NAD into the bloodstream through a small tube that is inserted into a vein.

What is the difference between NAD injections and NAD supplements?

The main difference between NAD injections and NAD supplements is the method of delivery. NAD injections involve injecting NAD directly into the bloodstream using a syringe, while NAD supplements are taken orally in the form of pills or capsules.

How to best self-administer a NAD injection?

When administering the injection, it is important to use a clean, sterile needle and syringe, and to inject the NAD into a vein using a slow, steady motion. It is also important to properly dispose of the used needles and syringes to avoid the risk of injury or infection. It is also important to carefully follow the instructions provided by the healthcare professional and the manufacturer of the NAD injection, including proper storage and handling of the injection and any necessary preparation steps.

NAD+ Nasal Spray

What are the benefits of NAD+ nasal spray?

NAD+ nasal spray is believed to have several potential benefits, including improving energy levels, supporting cognitive function, reducing inflammation, and supporting the body's natural detoxification processes.

What is the difference between NAD injection and NAD+ nasal spray?

The main difference between NAD injection and NAD+ nasal spray is the method of delivery. NAD injection involves injecting NAD directly into the bloodstream using a syringe, while NAD+ nasal spray involves delivering NAD directly into the bloodstream through the nose.

What is the difference between NAD+ nasal spray and NAD supplements?

The primary distinction between NAD+ nasal spray and NAD supplements is the route of administration. NAD+ nasal spray delivers NAD directly into the bloodstream via the nose, whereas NAD supplements are taken orally as tablets or capsules.

How often can I use the NAD+ nasal spray?

The frequency of NAD+ nasal spray use will depend on the specific product and the individual's needs and preferences. It is important to consult with a healthcare professional to determine the appropriate frequency of NAD+ nasal spray use, as well as any potential risks or side effects. In general, NAD+ nasal spray can be used daily or as needed, depending on the individual's goals and needs. It is also important to carefully follow the instructions provided by the healthcare professional and the manufacturer of the NAD+ nasal spray, including any recommended dosing guidelines and precautions.

What can I expect to feel after using the NAD+ nasal spray?

The effects of NAD+ nasal spray may vary depending on the individual and their unique physiology and health needs. In general, people may experience improved energy levels, cognitive function, and overall health and wellness after using NAD+ nasal spray. Additionally, NAD+ nasal spray may help to support the body's natural recovery processes and reduce the symptoms of conditions such as chronic fatigue syndrome, fibromyalgia, and addiction.

References

[1] Johnson S. - NAD + biosynthesis, aging, and disease.;

[2] Verdin E. - NAD⁺ in aging, metabolism, and neurodegeneration.;

[3] Zhao Y. - NAD+ improves cognitive function and reduces neuroinflammation by ameliorating mitochondrial damage and decreasing ROS production in chronic cerebral hypoperfusion models through Sirt1/PGC-1α pathway.;