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NAD+ IV Therapy: Benefits, Cost, And Side Effects

Many people rank health and wellness at the top of their list of priorities because they want to be healthier, perform better, and spend less time sick or recovering from the effects of aging. With the abundance of available options claiming to solve any health condition, it can be overwhelming to filter through them all, trying to determine which is right for you.

Happy smiling female receiving intravenous vitamin therapy in beauty clinic

NAD+ IV therapy stands above the rest in its effectiveness and innovative approach.

Today, we aim to provide an in-depth understanding of the benefits of NAD+ IV therapy:

  • The treatment itself
  • Any potential side effects
  • The most effective ways to receive NAD+

NAD's Role in Your Metabolism

NAD works on mitochondria and increases the length of telomeres, which are the protective caps located at the ends of chromosomes that become shorter as the body ages. NAD increases the activity of SIRT1 and PARP 1 proteins, which are linked with a slower rate of aging and influencing DNA repair respectively. – source

What is NAD+?

NAD+, short for nicotinamide adenine dinucleotide, is a coenzyme found in every cell in the body and plays a crucial role in cellular metabolism and energy production. It is a molecule composed of two nucleotides, nicotinamide and adenosine. Because it has a double-stranded structure, it is called a dinucleotide.

NAD+ is naturally occurring in the body and is formed from the essential nutrient niacin, also known as vitamin B3, through a process known as a nicotinamide salvage pathway. Cellular respiration acts as a “carrier” for electrons, allowing energy-rich molecules, like glucose, to send their electrons to the energy-making mitochondria. This transfer is essential for producing ATP (adenosine triphosphate), the body’s primary energy source.

As we age, the concentration of NAD+ levels in the body decreases, leading to a decline in energy production and cellular function.


Various factors, including oxidative stress, inflammation, poor diet, and lifestyle choices like excessive alcohol consumption, smoking, and a lack of physical activity, can cause this decrease in NAD+ levels.

How does NAD+ work?

NAD+ is found in all living cells and plays a crucial role in many biological processes in the body. It is involved in energy metabolism, DNA repair, and cellular communication.

The body uses NAD+ to maneuver electrons and energy along different metabolic pathways. It takes electrons from metabolic intermediates and gives them to the electron transport chain in the mitochondria, a process called oxidative metabolism. This process makes ATP, a form of energy cells that accomplish many different bodily functions.

NAD+ also plays a role in maintaining the integrity of DNA, as it is involved in DNA repair pathways, helping prevent genetic mutations and protecting against cell damage and deterioration. NAD+ also helps control circadian rhythms and keep sirtuins working. Sirtuins are a group of proteins that play a role in aging and living longer.

Supplementing NAD+ can positively affect health and wellness, including better energy production, communication between cells, and DNA repair. NAD+ IV infusions are more bioavailable than other forms of NAD, and they can effectively raise the amount of NAD+ in the body.

NAD+ benefits and uses

In recent years, much research has been conducted on NAD+, demonstrating how it can benefit health and wellness. NAD+ has been widely used to help individuals look and feel their best, but also for its potential in treating various diseases and disorders. Allow us to take a look at some of these benefits.


One of the most exciting benefits of NAD+ is its potential to slow down the aging process. NAD is a vital part of how cells manufacture energy and use it, and as we get older, our NAD levels tend to drop. This reduction in NAD levels is associated with cellular damage and age-related diseases. Taking NAD+ supplements can help restore NAD levels in the body, slowing down the aging process.

woman putting on cream and make up in front of the mirror

NAD+ can increase the lifespan of cells by boosting their energy production and repair mechanisms which, in turn, can help reduce the appearance of fine lines, wrinkles, and other signs of aging. NAD+ can also help increase the levels of other critical anti-aging molecules, such as sirtuins, which are known to extend the lifespan of cells.


NAD+ has tremendous medical potential in treating addiction, particularly alcohol and substance abuse. NAD+ helps control the brain’s reward and motivation centers, and insufficient levels can influence behaviors that are hard to stop. Supplementing with NAD+ can help to restore NAD levels in the brain and, as a result, may reduce the desire for addictive substances.

Person in distress holding head in hands

Studies have shown that NAD+ can reduce alcohol and substance cravings and improve overall mood and energy reserves. Because of this, NAD+ is an ideal choice for people who want to stop using drugs and improve their overall health and well-being.

Neurological disorders

NAD+ can potentially treat neurological disorders like depression, anxiety, and neurodegenerative diseases.1 NAD+ regulates neurotransmitter levels and energy metabolism in the brain, and its depletion has been linked to various neurological disorders. NAD+ can help to improve mood, reduce anxiety, and improve memory and cognitive function.

A woman holding a balloon with a smiley face on it

NAD+ can also help protect the brain against age-related decline and reduce the risk of neurodegenerative diseases such as Alzheimer’s and Parkinson’s.

Cardiovascular health

NAD+ has been found to play a crucial role in maintaining cardiovascular health. NAD+ helps control the heart’s energy production and metabolism, and its loss can contribute to heart problems with aging. Taking NAD+ supplements can help restore NAD levels in the heart and improve cardiovascular health.

red blood cells shaped in a heart

Studies have shown that NAD+ can improve blood flow, reduce inflammation, and lower cholesterol levels. NAD+ can reduce the risk of heart disease and stroke, making it a promising option for individuals looking to improve their cardiovascular health.

Metabolic disorders

Researchers have looked at NAD+ to see if it could help treat metabolic diseases like obesity and type 2 diabetes.

NAD+ supports the creation of energy and regulates energy usage, and a lack of it can develop metabolic disorders. Taking NAD+ supplements can help significantly restore NAD levels and improve metabolism. NAD+ can improve insulin sensitivity, reduce inflammation, and promote weight loss. NAD+ has also been found to reduce the risk of developing type 2 diabetes, making it a promising option.

obese woman holding her stomach


Inflammation is the body’s natural response to an injury or infection, but long-term inflammation can cause serious health problems. NAD+ may reduce inflammation to treat conditions like rheumatoid arthritis, Crohn’s disease, and ulcerative colitis. NAD+ may help lower the risk of getting chronic diseases in the first place by decreasing inflammation.

woman in blue dress touching her head like she's having a headache

Energy metabolism

NAD+ plays a critical role in energy metabolism as it helps transfer electrons from one molecule to another during cellular respiration. This process is necessary to make energy in the form of ATP, which cells use to do many different things. When NAD+ levels are low, energy production decreases, leading to fatigue, weakness, and decreased physical and mental performance.

NAD+ supplements restore energy levels, stimulating whole-body health and wellness, allowing us to achieve peak performance from our bodies.

happy woman jumping

DNA repair

NAD+ is involved in DNA repair, helping maintain our genetic material’s integrity.2 DNA damage has many culprits, from environmental toxins, radiation, and aging. By aiding in DNA repair, NAD+ can help reduce the risk of developing cancer and slow aging.

Ethnic woman with folded lips doing skin care procedure

Gene expression

Gene expression is how the information in our genes instructs our cells to perform specific operations or actions.

NAD+ plays an essential role in regulating gene expression, which can significantly impact overall health and wellness.

By supplementing with NAD+, people can influence the expression of genes that promote health while reducing the expression of genes that promote disease and aging.

Healthy Hair NAD Biotin

Cellular signaling

NAD+ is involved in cellular signaling, which is the process by which cells communicate with one another.

This communication is essential for maintaining normal cellular function and regulating the immune system, metabolism, and other critical physiological processes.

By taking NAD+ supplements, people can improve how cells talk to each other and promote optimal health and wellness.

human cell

NAD+ IV therapy

With its numerous benefits, NAD+ IV therapy has become popular among people who want to improve their overall health and wellness quickly and efficiently. NAD+ IV therapy involves putting NAD+ into the bloodstream through an IV, delivering a concentrated dose of the nutrient to the body.

Directly administering this treatment into the bloodstream helps the common problems other delivery mechanisms run into, such as oral supplements, which are not fully absorbed by the body. The fast delivery of NAD+ into the system makes it one of the most effective ways to get the nutrient into your body and ready to use immediately.

What is the cost of NAD+ IV therapy?

The cost of NAD+ IV therapy varies depending on several factors, including treatment formulations, add-ons, geographic location, and method of IV treatment. You can get treatment at a medical office or IV clinics. You can also get onsite infusions at home. In-home IV therapy saves time, eliminates the need for long commutes, and gives you a personalized experience in the comfort of your home.

With the convenience of in-home therapies, you can save time and have a medical professional come to your home to administer the treatment, giving you a more personalized and practical experience. Overall, the cost of NAD+ IV therapy will depend on several factors, but the growing trend of in-home treatments is becoming increasingly accessible and affordable to more people.

Are there side effects of NAD+ IV therapy?

NAD+ IV therapy is a promising therapy for many health issues, but like any medication or treatment, there is some risk of side effects. It is essential to know that even though NAD+ is generally considered safe and a natural part of the body, some people may still have side effects.

  • Headaches: can range from mild to severe, but the headaches usually go away within a few hours or days.
  • Nausea: This can be due to the rapid infusion of the nutrient into the body, which can cause the digestive system to become upset. Individuals who experience nausea should speak to their doctor, as they may be able to adjust the treatment to prevent this side effect.
  • Fatigue: Due to various factors, including a lack of adequate energy to properly metabolize this nutrient.
  • Dizziness: Some individuals may experience dizziness as a side effect of NAD+ IV therapy due to the rapid infusion of the nutrient into the body, which can suddenly cause blood pressure to drop.
  • Flushing: This may be due to the rapid infusion of the nutrient into the body, which can cause the blood vessels to dilate and cause redness and warmth in the face, neck, and chest.
  • Allergic reactions: Although rare, these are possible side effects of NAD+ IV therapy. These can include itching, redness, swelling, and hives.

Not all individuals will experience side effects from NAD+ IV therapy, and many have reported positive outcomes. If you have any concerns about the potential side effects of NAD+ IV therapy, you should speak to your doctor or a medical professional that can provide proper guidance.

Final thoughts

NAD+ plays a critical role in many vital processes within the body, including cellular energy production, DNA repair, gene expression, and more. Our NAD+ levels naturally drop as we age, which can negatively affect our health. The good news is that NAD+ IV therapy is a safe and effective way to restore these critical levels, which has several health and wellness benefits.

IV therapy is the most effective method for delivering NAD+ into the body, providing a high molecule concentration for immediate absorption into the bloodstream. While NAD+ IV therapy can be more expensive than other methods, it is convenient, time-saving, and allows for a personalized experience.

If you’re interested in learning more about NAD+ and the benefits of NAD+ IV therapy, don’t hesitate to reach out. Our team is always excited to discuss your options and help you start your journey to optimal health.

Take the First Step towards Better Health with NAD Therapy

Take control of your health and address your biggest health concerns with NAD therapy. Consult with a trusted medical professional today to explore the potential benefits of NAD and find personalized solutions for your unique needs.

  • Convenience
  • Comfort
  • Privacy
  • Personalized care
  • Flexible scheduling

Transform your health with NAD therapy and experience the life-changing benefits of personalized treatment tailored to your unique needs.

NAD - Frequently Asked Questions

What is NAD?

NAD is a coenzyme that is naturally produced by the body and is essential for various physiological processes, including energy production and DNA repair. It is found in all living cells and plays a critical role in many of the body's metabolic processes. NAD is a dinucleotide, which means that it consists of two nucleotides joined together. It is made up of two molecules: nicotinamide and adenine, which are joined together by a phosphate group.

NAD is involved in a wide range of biological processes, including the metabolism of carbohydrates, proteins, and fats, and is essential for the proper functioning of the body's cells and tissues.

What can I expect during a NAD IV treatment?

Our nurse will arrive at your location of choice with all the equipment necessary for the appointment. They will then administer the IV into your arm and stay with you to monitor the treatment and answer any questions you may have.

Our NAD IV treatments generally last couple of hours per session. You can sit back, watch a movie or a favorite show, browse social media, or even work while the treatment is in progress.

What sets Drip Hydration apart from other NAD IV treatment providers?

Drip Hydration brings appointments directly to you whether you are at home, at a hotel, or at the office. We make getting at home NAD IV treatments easy and convenient, saving you the time and hassle of sitting in traffic or waiting in a clinic.

Is NAD right for me?

You don’t have to wait until you are experiencing a medical condition to enjoy the benefits of NAD IV therapy. NAD plays a role in hundreds of chemical functions throughout your body. This versatile treatment helps promote whole-body wellness and can help your body maintain optimal performance over time.

Is IV therapy FDA approved?

IV therapy in general is FDA approved. Our nurses are overseen by our Medical Director, Abe Malkin, and every nurse is registered and certified per state standards.

Is NAD safe?

NAD is considered a dietary supplement, not a drug. The FDA does not currently evaluate dietary supplements in their current regulations. However, NAD is well-tolerated, meaning that there are rarely side effects.

How long do IV treatments take?

Our IV NAD treatments take couple of hours to administer per session. The number of sessions vary by individual and will be determined during your initial consultation.

Does NAD help battle aging?

Some studies have suggested that NAD may have anti-aging effects by helping to support the production of enzymes that are involved in DNA repair and maintenance, which are essential for maintaining healthy cells and tissues. Additionally, NAD may support the production of enzymes that are involved in the body's natural detoxification processes, which can help to reduce the effects of oxidative stress and support healthy aging. 

Does NAD Improve metabolic function?

Some studies have suggested that NAD may support healthy metabolism by helping to regulate the body's energy production and utilization, and may also support the production of enzymes that are involved in various metabolic processes. Additionally, NAD may support the body's natural detoxification processes, which are important for maintaining overall health and wellness.

How often can I get an NAD treatment?

NAD IV treatments are most effective when used over time. You can get treatments several times per month unless you are otherwise advised during your initial consultation.

What can I expect to feel after a NAD IV drip?

Following a NAD IV drip, most patients feel more energetic, clearer-headed, and focused. Regular treatments may improve these effects over time.

Is there any downtime or recovery after a NAD drip?

Not at all! You can resume your normal activities immediately after your appointment. Where do you deliver NAD IV treatments? Drip Hydration delivers NAD IV treatments anywhere within our service areas, which you can find on our service area pages. That said, we recommend choosing a comfortable place for NAD treatments since this type of IV takes couple of hours per appointment.

How is IV NAD better than an oral NAD supplement?

IV NAD is delivered directly into your bloodstream, where it becomes available to your cells for immediate use. Because NAD bypasses the digestive and metabolic systems, you can expect a 100% absorption rate for maximum effect and minimal waste. Oral NAD supplements, on the other hand, must pass through your digestive system, where they are partly metabolized before your body has access to orally given NAD.

What is the difference between a NAD IV and a vitamin drip?

There are two main differences between a NAD IV and a Vitamin Drip: duration and ingredients. NAD IVs generally take couple of hours to administer per session while vitamin drips take 30 - 45 minutes. Our vitamin drips are specially blended to improve a variety of symptoms and ailments. Our NAD+ Boost treatments contains vitamins that can help make this IV more effective with longer-lasting effects.

Do I need any special supplies for my NAD IV appointment?

No, you do not need any special supplies. Our nurse will bring everything needed for the appointment.

Does NAD improve brain health and function?

NAD is believed to have potential benefits for brain health and function, although more research is needed to fully understand its effects. Some studies have suggested that NAD may have neuroprotective effects, meaning that it may help to protect the brain from damage and support healthy brain function. Additionally, NAD may support the production of neurotransmitters, which are chemicals that help to transmit signals between the brain's cells, and may help to improve cognitive function and memory.