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What is a NAD Shot, and How Can it Support Your Health?

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On the search for a new and effective way to boost your energy, mood, and overall health?

Also known as NAD injections, NAD shots are becoming increasingly popular among people looking for a natural way to improve well-being. But what exactly is NAD, and how can NAD shots help optimize your health?

In this article, we’ll explore the benefits and uses of a NAD shot while providing you with the information needed to decide whether it is the right choice for you.

Order NAD+ Injections

NAD is essential to cellular health, but levels decline as we age. We offer self-administered NAD+ injections to replenish NAD levels, which may offer a variety of anti-aging benefits.

How can NAD Shots Help Support Your Health?

Nicotinamide adenine dinucleotide (NAD+) is a molecule that plays a vital role in many metabolic functions, such as energy production and DNA repair. NAD is a critical component in cell metabolism1 and is vital in energy production, cognitive function, and other processes. Normal NAD levels naturally decline as we age, leading to reduced cell function and increased inflammation.

Increasing NAD levels through a NAD shot may offer a wide range of benefits for health and wellness. NAD injections deliver a dose of NAD directly into muscle tissue or fatty tissue near the site of injury or chronic pain, allowing the treatment to access body tissues and stimulate the healing process immediately.

NAD shots can help increase energy levels and improve mental clarity because NAD produces ATP, the molecule responsible for providing cells with energy. This therapy can improve energy production by boosting NAD levels. NAD has been shown to have:

  • Anti-aging2 and anti-inflammatory3 effects.
  • Positive impacts on mood, sleep, and cognitive function4
  • A role in regulating neurotransmitters such as serotonin and dopamine, which are involved in mood regulation and stress management.
Graceful ageing

Comparing NAD Shots to other Forms of NAD Supplementation

NAD can be administered in various ways depending on the patient’s needs and preferences. These include intravenous (IV) infusions, intramuscular injections, subcutaneous injections, nasal sprays, and oral supplements.

NAD IV Therapy

NAD IV therapies involve administering NAD directly into the vein and have a rapid onset.

This method benefits people who need to replenish their NAD levels quickly, as the process is timely, and the therapeutic effects can take an impact within minutes of administration.

NAD Nasal Sprays

Nasal sprays are one of the newer forms of NAD supplementation. This method involves spraying a specially formulated solution containing NAD molecules directly into the nasal cavity. This method is advantageous as the NAD molecules are quickly absorbed and can get to work fast, relieving chronic pain or other conditions.

NAD Oral supplements

Oral supplements do not typically require a prescription and can often be purchased at pharmacies and through online retailers. Supplements may be taken once or more per day, depending on the manufacturer’s instructions. Although this option is convenient and affordable, oral supplements are not 100% bioavailable due to some components being lost to the digestive process.

NAD Injections

Injections are administered in a single dose, providing quick relief and lasting effects.

  • Intramuscular injections involve injecting NAD directly into the muscle and can provide a rapid onset of effects. This method is ideal for those looking to replenish their NAD levels quickly or have difficulty with IV access.
  • Subcutaneous injections involve injecting the NAD just beneath the skin and provide a slower onset of effects. This method is best suited for those who do not need a rapid onset of results, as it can take several hours to feel the effects.

Regardless of which method you choose, any NAD supplement can be incredibly effective at helping restore NAD levels and providing numerous benefits to patients.

Energy Person Jump Happy Nad Therapy

However, before beginning any treatment, you must speak with your healthcare provider about the best option.

Who should Consider NAD Shots?

NAD shots may be beneficial for aging adults, especially those with a family history of age-related neurological conditions. NAD plays a vital role in regulating brain activity and communication, which helps keep cognitive functioning balanced.

Taking a NAD shot regularly can provide a source of consistent NAD, which may slow down the effects of aging and neurological decline. For individuals with chronic health conditions, NAD shots may also be beneficial because NAD is a key molecule involved in metabolic pathways such as:

NAD shots can help support these pathways and improve overall health by providing a steady supply of NAD.

metabolism atp creation, illustration

Lastly, a NAD shot can also be a preventative measure for overall health and wellness, providing essential nutrients that may otherwise be lacking in the diet and helping maximize energy levels and alertness. Additionally, it can help protect against free radical damage and reduce inflammation that can lead to chronic diseases.

NAD shots may benefit athletes, busy professionals, aging adults, 5 and individuals with chronic health conditions looking to optimize their health and wellness. However, you must consult your doctor before considering NAD shots to ensure they are the right choice for you.

Potential NAD Shot Side Effects

In most cases, NAD shots are well-tolerated, with a low risk of serious side effects or complications.

Common side effects of a NAD shot:

dizzy side effect efect
  • Mild nausea
  • Headaches
  • Dizziness
  • Fatigue

Although some side effects may be mild, such as mild discomfort or fatigue after the injection, these usually pass shortly after and do not require medical attention. Some individuals should not use NAD, including individuals with existing health conditions such as kidney or liver disease, diabetes, or hypertension, pregnant or breastfeeding women, and those taking certain prescription medications.

If you experience complications or severe side effects after receiving a NAD shot, seek medical attention immediately. Also, please consult your healthcare provider about the risks and benefits of using NAD shots to ensure they are the right choice.

Overall, the benefits of NAD shots, including improved energy levels and enhanced mental clarity, often outweigh any minor discomforts accompanying this treatment. In addition, medical supervision of NAD shots minimizes the risk of adverse effects.


NAD shots can help supplement your body with NAD, an essential molecule involved in metabolism. These shots help provide:

  • Increased energy
  • Improved cognitive functions
  • Improved sleep
  • Better overall mood

The treatment process is quick and efficient, allowing for rapid absorption of NAD. While NAD shots can benefit many people, always consult a physician before taking them, as there may be some side effects, potential allergies, or medications that could interact with the treatment.

Get a NAD+ Injections

NAD is essential to cellular health, but levels decline as we age. We offer self-administered NAD+ injections to replenish NAD levels, which may offer a variety of anti-aging benefits.

Schedule an appointment, and we will guide you through the process and prescribe you the medication.

NAD - Frequently Asked Questions

What is NAD?

NAD is a coenzyme that is naturally produced by the body and is essential for various physiological processes, including energy production and DNA repair. It is found in all living cells and plays a critical role in many of the body's metabolic processes. NAD is a dinucleotide, which means that it consists of two nucleotides joined together. It is made up of two molecules: nicotinamide and adenine, which are joined together by a phosphate group.

NAD is involved in a wide range of biological processes, including the metabolism of carbohydrates, proteins, and fats, and is essential for the proper functioning of the body's cells and tissues.

What can I expect during a NAD IV treatment?

Our nurse will arrive at your location of choice with all the equipment necessary for the appointment. They will then administer the IV into your arm and stay with you to monitor the treatment and answer any questions you may have.

Our NAD IV treatments generally last 3 - 4 hours per session. You can sit back, watch a movie or a favorite show, browse social media, or even work while the treatment is in progress.

What sets Drip Hydration apart from other NAD IV treatment providers?

Drip Hydration brings appointments directly to you whether you are at home, at a hotel, or at the office. We make getting at home NAD IV treatments easy and convenient, saving you the time and hassle of sitting in traffic or waiting in a clinic.

Is NAD right for me?

You don’t have to wait until you are experiencing a medical condition to enjoy the benefits of NAD IV therapy. NAD plays a role in hundreds of chemical functions throughout your body. This versatile treatment helps promote whole-body wellness and can help your body maintain optimal performance over time.

Is IV therapy FDA approved?

IV therapy in general is FDA approved. Our nurses are overseen by our Medical Director, Abe Malkin, and every nurse is registered and certified per state standards.

Is NAD safe?

NAD is considered a dietary supplement, not a drug. The FDA does not currently evaluate dietary supplements in their current regulations. However, NAD is well-tolerated, meaning that there are rarely side effects.

How long do IV treatments take?

Our IV NAD treatments take between 3 - 4 hours to administer per session. The number of sessions vary by individual and will be determined during your initial consultation.

Does NAD help battle aging?

Some studies have suggested that NAD may have anti-aging effects by helping to support the production of enzymes that are involved in DNA repair and maintenance, which are essential for maintaining healthy cells and tissues. Additionally, NAD may support the production of enzymes that are involved in the body's natural detoxification processes, which can help to reduce the effects of oxidative stress and support healthy aging. 

Does NAD improve brain health and function?

NAD is believed to have potential benefits for brain health and function, although more research is needed to fully understand its effects. Some studies have suggested that NAD may have neuroprotective effects, meaning that it may help to protect the brain from damage and support healthy brain function. Additionally, NAD may support the production of neurotransmitters, which are chemicals that help to transmit signals between the brain's cells, and may help to improve cognitive function and memory.

Do I need any special supplies for my NAD IV appointment?

No, you do not need any special supplies. Our nurse will bring everything needed for the appointment.

Does NAD Improve metabolic function?

Some studies have suggested that NAD may support healthy metabolism by helping to regulate the body's energy production and utilization, and may also support the production of enzymes that are involved in various metabolic processes. Additionally, NAD may support the body's natural detoxification processes, which are important for maintaining overall health and wellness.

How often can I get an NAD treatment?

NAD IV treatments are most effective when used over time. You can get treatments several times per month unless you are otherwise advised during your initial consultation.

What can I expect to feel after a NAD IV drip?

Following a NAD IV drip, most patients feel more energetic, clearer-headed, and focused. Regular treatments may improve these effects over time.

Is there any downtime or recovery after a NAD drip?

Not at all! You can resume your normal activities immediately after your appointment. Where do you deliver NAD IV treatments? Drip Hydration delivers NAD IV treatments anywhere within our service areas, which you can find on our service area pages. That said, we recommend choosing a comfortable place for NAD treatments since this type of IV takes 3 - 4 hours per appointment.

How is IV NAD better than an oral NAD supplement?

IV NAD is delivered directly into your bloodstream, where it becomes available to your cells for immediate use. Because NAD bypasses the digestive and metabolic systems, you can expect a 100% absorption rate for maximum effect and minimal waste. Oral NAD supplements, on the other hand, must pass through your digestive system, where they are partly metabolized before your body has access to orally given NAD.

What is the difference between a NAD IV and a vitamin drip?

There are two main differences between a NAD IV and a Vitamin Drip: duration and ingredients. NAD IVs generally take 3 - 4 hours to administer per session while vitamin drips take 30 - 45 minutes. Our vitamin drips are specially blended to improve a variety of symptoms and ailments. Our NAD+ Boost treatments contains vitamins that can help make this IV more effective with longer-lasting effects.

What are the benefits of NAD Injection Therapy?

NAD injection therapy is believed to have several potential benefits, including improving energy levels, supporting cognitive function, reducing inflammation, and supporting the body's natural detoxification processes. Additionally, NAD injection therapy is often used in combination with other treatments, such as IV vitamin therapy, to support the body's natural recovery processes and improve overall health and wellness.

What is the difference between NAD injection vs NAD IV therapy?

The main difference between NAD injection and NAD IV therapy is the method of delivery. NAD injection involves injecting NAD directly into the bloodstream using a syringe, while NAD IV therapy involves infusing NAD into the bloodstream through a small tube that is inserted into a vein.

What is the difference between NAD injections and NAD supplements?

The main difference between NAD injections and NAD supplements is the method of delivery. NAD injections involve injecting NAD directly into the bloodstream using a syringe, while NAD supplements are taken orally in the form of pills or capsules.

How to best self-administer a NAD injection?

When administering the injection, it is important to use a clean, sterile needle and syringe, and to inject the NAD into a vein using a slow, steady motion. It is also important to properly dispose of the used needles and syringes to avoid the risk of injury or infection. It is also important to carefully follow the instructions provided by the healthcare professional and the manufacturer of the NAD injection, including proper storage and handling of the injection and any necessary preparation steps.


[1] Covarrubias AJ, Perrone R, Grozio A, et al. - NAD+ metabolism and its roles in cellular processes during ageing. Nat Rev Mol Cell Biol. 2021 Feb;22(2):119-141. doi: 10.1038/s41580-020-00313-x;

[2] Verdin E. - NAD⁺ in aging, metabolism, and neurodegeneration. Science. 2015 Dec 4;350(6265):1208-13. doi: 10.1126/science.aac4854;

[3] Braidy N, Liu Y. - NAD+ therapy in age-related degenerative disorders: A benefit/risk analysis. Exp Gerontol. 2020 Apr;132:110831. doi: 10.1016/j.exger.2020.110831;

[4] Zhao Y, Zhang J, Zheng Y, et al. - NAD+ improves cognitive function and reduces neuroinflammation by ameliorating mitochondrial damage and decreasing ROS production in chronic cerebral hypoperfusion models through Sirt1/PGC-1α pathway. J Neuroinflammation. 2021 Sep 16;18(1):207. doi: 10.1186/s12974-021-02250-8;

[5] Reiten OK, Wilvang MA, Mitchell SJ, et al. - Preclinical and clinical evidence of NAD+ precursors in health, disease, and ageing. Published on Oct 2021. Mechanisms of Ageing and Development Volume 199, 111567, ISSN 0047-6374. https://doi.org/10.1016/j.mad.2021.111567;