NAD IV Therapy For Anti-Aging

Nicotinamide adenine dinucleotide (NAD+) is a powerful coenzyme naturally occurring in our bodies that plays a vital role in several essential cellular processes, including energy production, DNA repair, and gene expression.

As we age, our NAD+ levels naturally decline, contributing to various age-related changes and potential health issues. Intravenous (IV) NAD+ therapy is an emerging approach that aims to boost NAD+ levels, potentially supporting healthy aging and various aspects of physiological function.

Research suggests that NAD+ may play a role in:

  • Energy Levels: NAD+ is essential for cellular energy production, and maintaining adequate levels may help support energy levels and combat fatigue.
  • Mood: NAD+ influences neurotransmitter production, potentially impacting mood regulation and mental well-being.
    Athletic Performance: Some studies suggest that NAD+ may enhance exercise performance and recovery by supporting energy metabolism and mitochondrial function.
  • Cognitive Function: NAD+ is crucial for brain health, and maintaining optimal levels may support cognitive function and potentially mitigate age-related cognitive decline.

While NAD+ shows promise in supporting healthy aging and addressing various health concerns, it’s important to consult with a healthcare professional to discuss the potential benefits, risks, and appropriate treatment options for your specific needs.

  • Belenky, P., Bogan, K. L., & Brenner, C. (2007). NAD+ metabolism in health and disease. Trends in Biochemical Sciences, 32(1), 12-19.
  • Braidy, N., Berg, J., Clement, J., Khorshidi, F., Poljak, A., Jayasena, T., Grant, R., & Sachdev, P. (2019). Role of Nicotinamide Adenine Dinucleotide and Related Precursors as Therapeutic Targets for Age-Related Degenerative Diseases: Rationale, Biochemistry, Pharmacokinetics, and Outcomes. Antioxidants & redox signaling, 30(2), 251–294. https://doi.org/10.1089/ars.2017.7269
  • Covarrubias, A. J., Perrone, R., Grozio, A., & Verdin, E. (2021). NAD(+) metabolism and its roles in cellular processes during aging. Nature Reviews Molecular Cell Biology, 22(2), 119-141.
  • Grant, R., Berg, J., Mestayer, R., Braidy, N., Bennett, J., Broom, S., … & Guillemin, G. J. (2020). A pilot study investigating changes in neural metabolites associated with intravenous NAD+ administration in humans. Frontiers in Aging Neuroscience, 12, 36.
  • Kane, A. E., & Sinclair, D. A. (2018). Sirtuins and NAD+ in the development and treatment of metabolic and cardiovascular diseases. Circulation Research, 123(7), 868-885.
  • Lautrup, S., Sinclair, D. A., Mattson, M. P., & Fang, E. F. (2019). NAD+ in brain aging and neurodegenerative disorders. Cell Metabolism, 30(4), 630-655.
  • Schultz, M. B., & Sinclair, D. A. (2016). Why NAD(+) declines during aging: It’s destroyed. Cell Metabolism, 23(6), 965-966.
  • Yoshino, J., Mills, K. F., Yoon, M. J., & Imai, S. (2011). Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice. Cell Metabolism, 14(4), 528-536.

NAD's Role in Your Metabolism

NAD works on mitochondria and increases the length of telomeres, which are the protective caps located at the ends of chromosomes that become shorter as the body ages. NAD increases the activity of SIRT1 and PARP 1 proteins, which are linked with a slower rate of aging and influencing DNA repair respectively. – source

Driphydration Nad Therapy Get NAD

What is NAD+?

Nicotinamide adenine dinucleotide (NAD+) is a crucial coenzyme found in all living cells, including those of mammals. It exists in two forms, oxidized (NAD+) and reduced (NADH), both of which play essential roles in cellular function. NAD+ acts as an electron acceptor in various metabolic reactions, particularly in energy production, while NADH functions as a potent antioxidant, helping to neutralize harmful free radicals.

As we age, NAD+ levels naturally decline, contributing to various age-related physiological changes and potentially increasing susceptibility to certain diseases.

Research is ongoing to explore the potential benefits of NAD+ supplementation in various areas, including age-related decline, cognitive function, metabolic health, and physical performance. However, more studies are needed to fully understand the effects of NAD+ supplementation and its long-term implications.

It’s important to consult with a healthcare professional before considering NAD+ supplementation to discuss its potential benefits and risks, as well as appropriate dosage and delivery methods.

  • Belenky, P., Bogan, K. L., & Brenner, C. (2007). NAD+ metabolism in health and disease. Trends in Biochemical Sciences, 32(1), 12-19.
  • Fang, E. F., Scheibye-Knudsen, M., Brace, L. E., Kassahun, H., SenGupta, T., Nilsen, H., Mitchell, J. R., Croteau, D. L., & Bohr, V. A. (2014). Defective mitophagy in XPA via PARP-1 hyperactivation and NAD(+)/SIRT1 reduction. Cell, 157(4), 882–896. https://doi.org/10.1016/j.cell.2014.03.026
  • Yoshino, J., Mills, K. F., Yoon, M. J., & Imai, S. (2011). Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice. Cell Metabolism, 14(4), 528-536. 4. Braidy, N., Berg, J., & Clement, J. (2021). Clinical applications of NAD+ and its precursors. Frontiers in Medicine, 8, 313.

What is NAD+ IV Therapy?

NAD+ IV therapy delivers NAD+ directly into the bloodstream, bypassing the digestive system, which may result in higher bioavailability compared to oral supplements, as some NAD+ can be degraded in the digestive tract before absorption. This means that a larger proportion of the administered dose may be available to the body’s cells.

nomenclature-nad

Due to the direct delivery into the bloodstream, IV NAD+ therapy may also offer a faster onset of action than oral supplements. However, the overall effectiveness and specific benefits of each delivery method can vary depending on individual factors and health goals.

It’s crucial to consult with a healthcare professional to discuss the potential benefits and risks of different NAD+ delivery methods and to determine the most appropriate approach for your individual needs.

  • Braidy, N., Berg, J., Clement, J., Khorshidi, F., Poljak, A., Jayasena, T., Grant, R., & Sachdev, P. (2019). Role of Nicotinamide Adenine Dinucleotide and Related Precursors as Therapeutic Targets for Age-Related Degenerative Diseases: Rationale, Biochemistry, Pharmacokinetics, and Outcomes. Antioxidants & redox signaling, 30(2), 251–294. https://doi.org/10.1089/ars.2017.7269
  • Trammell, S. A., Schmidt, M. S., Weidemann, B. J., Redpath, P., Jaksch, F., Dellinger, R. W., … & Brenner, C. (2016). Nicotinamide riboside is uniquely and orally bioavailable in mice and humans. Nature Communications, 7(1), 1-12.
    Yoshino, J., Mills, K. F., Yoon, M. J., & Imai, S. (2011). Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice. Cell Metabolism, 14(4), 528-536.

What is in an NAD+ IV Therapy Formula?

At Drip Hydration, our NAD+ IV therapy is formulated to deliver optimal quantities of nicotinamide adenine dinucleotide to provide the best possible outcomes. Additionally, the NAD+ supplement formula is enhanced with other conjunctional super nutrients to offer even more health benefits.

Here is a breakdown of what you can expect your NAD+ IV therapy formula to contain:

  • IV Fluids: A sterile saline solution containing a combination of selected nutrients delivered directly into the bloodstream, bypassing the digestive system and potentially enhancing absorption
  • NAD+: A coenzyme essential for cellular energy production and other vital functions, with research suggesting potential benefits in various areas, including aging and cognitive function. The appropriate dosage is determined by a healthcare professional based on individual needs.
  • Vitamin B12: An essential vitamin for neurological function and red blood cell production, which may help alleviate fatigue and cognitive impairment associated with deficiency.
  • B-Complex Vitamins: A group of essential vitamins that play various roles in energy metabolism, immune function, and other physiological processes, potentially supporting overall health and well-being.
two women getting IV therapy at their home
  • Vitamin C: An antioxidant vitamin involved in numerous bodily functions, including immune response, collagen synthesis, and wound healing.
  • Glutathione: A powerful antioxidant naturally produced in the body, contributing to detoxification and protection against oxidative stress.
  • Belenky, P., Bogan, K. L., & Brenner, C. (2007). NAD+ metabolism in health and disease. Trends in Biochemical Sciences, 32(1), 12-19.
  • Braidy, N., Berg, J., Clement, J., Khorshidi, F., Poljak, A., Jayasena, T., Grant, R., & Sachdev, P. (2019). Role of Nicotinamide Adenine Dinucleotide and Related Precursors as Therapeutic Targets for Age-Related Degenerative Diseases: Rationale, Biochemistry, Pharmacokinetics, and Outcomes. Antioxidants & redox signaling, 30(2), 251–294. https://doi.org/10.1089/ars.2017.7269
  • Campbel, A. (2016) The IV Manual: An Evidence-Based Guide to Intravenous Therapy. Australian Injectable Drugs Handbook Pty Ltd.
  • Carr, A. C., & Maggini, S. (2017). Vitamin C and immune function. Nutrients, 9(11), 1211.
  • Forman, H. J., Zhang, H., & Rinna, A. (2009). Glutathione: overview of its protective roles, measurement, and biosynthesis. Molecular aspects of medicine, 30(1-2), 1-12.
  • Kennedy, D. O. (2016). B Vitamins and the Brain: Mechanisms, Dose and Efficacy–A Review. Nutrients, 8(2), 68.
  • Office of Dietary Supplements – Vitamin B12. (2022, March 26). Retrieved from https://ods.od.nih.gov/factsheets/vitaminb12-healthprofessional/

Why Get NAD+ IV Therapy for Anti-Aging?

Nicotinamide adenine dinucleotide (NAD+) is a vital coenzyme that plays a central role in cellular energy production. It is involved in various metabolic processes and supports the function of mitochondria, the powerhouses of our cells. NAD+ levels naturally decline with age, and this decline has been linked to various age-related conditions and diseases, including neurodegenerative and metabolic disorders.

Research is ongoing to explore the potential therapeutic applications of NAD+ in addressing age-related decline, cognitive impairment, metabolic dysfunction, and other health conditions in humans. Some studies suggest that replenishing NAD+ levels through IV therapy may offer benefits such as:

  • Supporting cellular energy production and potentially improving fatigue.
  • Promoting DNA repair and potentially mitigating the effects of aging.
  • Modulating inflammation and potentially protecting against neurodegeneration.
  • Supporting mitochondrial function, which is crucial for cellular health.

While NAD+ therapy shows promise, it’s important to consult with a healthcare professional to discuss the potential benefits, risks, and appropriate treatment options for your specific needs. More research is needed to fully understand the long-term effects and efficacy of NAD+ therapy in various conditions.

  • Amjad, S., Nisar, S., Bhat, A. A., Shah, A. R., Frenneaux, M. P., Fakhro, K., Haris, M., Reddy, R., Patay, Z., Baur, J., & Bagga, P. (2021). Role of NAD+ in regulating cellular and metabolic signaling pathways. Molecular metabolism, 49, 101195. https://doi.org/10.1016/j.molmet.2021.101195
  • Belenky, P., Bogan, K. L., & Brenner, C. (2007). NAD+ metabolism in health and disease. Trends in Biochemical Sciences, 32(1), 12-19.
  • Braidy, N., Berg, J., Clement, J., Khorshidi, F., Poljak, A., Jayasena, T., Grant, R., & Sachdev, P. (2019). Role of Nicotinamide Adenine Dinucleotide and Related Precursors as Therapeutic Targets for Age-Related Degenerative Diseases: Rationale, Biochemistry, Pharmacokinetics, and Outcomes. Antioxidants & redox signaling, 30(2), 251–294. https://doi.org/10.1089/ars.2017.7269
  • Fang, E. F., Scheibye-Knudsen, M., Brace, L. E., Kassahun, H., SenGupta, T., Nilsen, H., … & Bohr, V. A. (2016). Defective mitophagy in XPA via PARP-1 hyperactivation and NAD(+)/SIRT1 reduction. Cell, 167(4), 882-896.
  • Lautrup, S., Sinclair, D. A., Mattson, M. P., & Fang, E. F. (2019). NAD+ in brain aging and neurodegenerative disorders. Cell Metabolism, 30(4), 630-655.
  • Newman, J. C., He, W., & Verdin, E. (2012). Mitochondrial protein acylation and intermediary metabolism: regulation by sirtuins and implications for metabolic disease. The Journal of biological chemistry, 287(51), 42436–42443. https://doi.org/10.1074/jbc.R112.404863
  • Yoshino, J., Mills, K. F., Yoon, M. J., & Imai, S. (2011). Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice. Cell Metabolism, 14(4), 528-536.

How Long Does NAD+ IV Therapy Take?

When you schedule an NAD+ IV, the treatment will be organized as a multi-week treatment plan with multiple IVs administered throughout the treatment.

How Does A NAD+ Delivery IV Appointment Work?

Our NAD+ IV therapy treatments are simple and convenient. When you book an appointment, our nurse will come to your desired location with all the necessary equipment, so you will not need to get anything for the appointment.

The nurse will then set up the IV and position the IV bag over your head, a well-accepted practice in the medical field as it utilizes gravity to drip the IV contents into your arm. We recommend having a comfortable chair or sofa that you can sit in as the IV is administered. The nurse will then connect the IV bag to your arm via a slender catheter and tubing.

Once set up, all you need to do is sit back and relax as the IV fluid enters your bloodstream. We recommend planning some passive activities to do during the session. You could watch TV, read a book, or do anything else that you can enjoy while seated. Our nurse will be on hand to monitor the entire process.

Where Do You Deliver NAD+ IV Therapy?

As a flexible and dynamic delivery service, Drip’s NAD+ IV therapy can be delivered to any location you currently are. This includes, but is not limited to, your office, health club, home, spa, tour bus, gym, hotel, festival, private event, or virtually any other location. Our only requirement is that the location has a comfortable and stationary space where we can set up the IV and administer it with no interruptions. Give us a call, and we’ll be happy to help you get the treatment you need where you want.

How Often Can You Get NAD IV Therapy for Anti-Aging?

The frequency of NAD+ IV therapy for anti-aging can vary depending on individual needs and goals. A typical approach involves multiple infusions over several weeks to achieve a cumulative effect and promote cellular repair and regeneration. After the initial course of treatment, some individuals may choose to receive periodic booster infusions to maintain the potential benefits, although the optimal frequency for maintenance treatments is still under investigation.

The frequency of NAD+ IV therapy should be determined in consultation with a qualified healthcare professional. They can assess your individual health status, goals, and response to treatment to tailor a personalized NAD+ therapy plan that maximizes benefits while minimizing potential risks.

It’s important to note that NAD+ IV therapy is not a magic bullet for anti-aging. While it may offer potential benefits in supporting cellular health and function, a comprehensive approach to healthy aging involves various lifestyle factors, including a balanced diet, regular exercise, stress management, and adequate sleep.

  • Braidy, N., Berg, J., Clement, J., Khorshidi, F., Poljak, A., Jayasena, T., Grant, R., & Sachdev, P. (2019). Role of Nicotinamide Adenine Dinucleotide and Related Precursors as Therapeutic Targets for Age-Related Degenerative Diseases: Rationale, Biochemistry, Pharmacokinetics, and Outcomes. Antioxidants & redox signaling, 30(2), 251–294. https://doi.org/10.1089/ars.2017.7269
  • Martens, C. R., Denman, B. A., Mazzo, M. R., Armstrong, M. L., Reisdorph, N., McQueen, M. B., … & Seals, D. R. (2018). Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults. Nature Communications, 9(1), 1286.
  • Shade, C. (2020). The science behind NAD+: Nicotinamide adenine dinucleotide (NAD+) is an essential coenzyme found in all living cells. It plays a vital role in cellular energy production, DNA repair, and gene expression. Integrative Medicine: A Clinician’s Journal, 19(1), 12–14.
  • Yoshino, J., Mills, K. F., Yoon, M. J., & Imai, S. (2011). Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice. Cell Metabolism, 14(4), 528-536.

Take the First Step towards Better Health with NAD Therapy

Take control of your health and address your biggest health concerns with NAD therapy. Consult with a trusted medical professional today to explore the potential benefits of NAD and find personalized solutions for your unique needs.

  • Convenience
  • Comfort
  • Privacy
  • Personalized care
  • Flexible scheduling

Transform your health with NAD therapy and experience the life-changing benefits of personalized treatment tailored to your unique needs.

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NAD - Frequently Asked Questions

What is NAD?

NAD is a coenzyme that is naturally produced by the body and is essential for various physiological processes, including energy production and DNA repair. It is found in all living cells and plays a critical role in many of the body's metabolic processes. NAD is a dinucleotide, which means that it consists of two nucleotides joined together. It is made up of two molecules: nicotinamide and adenine, which are joined together by a phosphate group.

NAD is involved in a wide range of biological processes, including the metabolism of carbohydrates, proteins, and fats, and is essential for the proper functioning of the body's cells and tissues.

What can I expect during a NAD IV treatment?

Our nurse will arrive at your location of choice with all the equipment necessary for the appointment. They will then administer the IV into your arm and stay with you to monitor the treatment and answer any questions you may have.

Our NAD IV treatments generally last couple of hours per session. You can sit back, watch a movie or a favorite show, browse social media, or even work while the treatment is in progress.

What sets Drip Hydration apart from other NAD IV treatment providers?

Drip Hydration brings appointments directly to you whether you are at home, at a hotel, or at the office. We make getting at home NAD IV treatments easy and convenient, saving you the time and hassle of sitting in traffic or waiting in a clinic.

Is NAD right for me?

You don’t have to wait until you are experiencing a medical condition to enjoy the benefits of NAD IV therapy. NAD plays a role in hundreds of chemical functions throughout your body. This versatile treatment helps promote whole-body wellness and can help your body maintain optimal performance over time.

Is IV therapy FDA approved?

IV therapy in general is FDA approved. Our nurses are overseen by our Medical Director, Abe Malkin, and every nurse is registered and certified per state standards.

Is NAD safe?

NAD is considered a dietary supplement, not a drug. The FDA does not currently evaluate dietary supplements in their current regulations. However, NAD is well-tolerated, meaning that there are rarely side effects.

How long do IV treatments take?

Our IV NAD treatments take couple of hours to administer per session. The number of sessions vary by individual and will be determined during your initial consultation.

Does NAD help battle aging?

Some studies have suggested that NAD may have anti-aging effects by helping to support the production of enzymes that are involved in DNA repair and maintenance, which are essential for maintaining healthy cells and tissues. Additionally, NAD may support the production of enzymes that are involved in the body's natural detoxification processes, which can help to reduce the effects of oxidative stress and support healthy aging. 

How often can I get an NAD treatment?

NAD IV treatments are most effective when used over time. You can get treatments several times per month unless you are otherwise advised during your initial consultation.

What can I expect to feel after a NAD IV drip?

Following a NAD IV drip, most patients feel more energetic, clearer-headed, and focused. Regular treatments may improve these effects over time.

Is there any downtime or recovery after a NAD drip?

Not at all! You can resume your normal activities immediately after your appointment. Where do you deliver NAD IV treatments? Drip Hydration delivers NAD IV treatments anywhere within our service areas, which you can find on our service area pages. That said, we recommend choosing a comfortable place for NAD treatments since this type of IV takes couple of hours per appointment.

How is IV NAD better than an oral NAD supplement?

IV NAD is delivered directly into your bloodstream, where it becomes available to your cells for immediate use. Because NAD bypasses the digestive and metabolic systems, you can expect a 100% absorption rate for maximum effect and minimal waste. Oral NAD supplements, on the other hand, must pass through your digestive system, where they are partly metabolized before your body has access to orally given NAD.

What is the difference between a NAD IV and a vitamin drip?

There are two main differences between a NAD IV and a Vitamin Drip: duration and ingredients. NAD IVs generally take couple of hours to administer per session while vitamin drips take 30 - 45 minutes. Our vitamin drips are specially blended to improve a variety of symptoms and ailments. Our NAD+ Boost treatments contains vitamins that can help make this IV more effective with longer-lasting effects.

Do I need any special supplies for my NAD IV appointment?

No, you do not need any special supplies. Our nurse will bring everything needed for the appointment.

Does NAD Improve metabolic function?

Some studies have suggested that NAD may support healthy metabolism by helping to regulate the body's energy production and utilization, and may also support the production of enzymes that are involved in various metabolic processes. Additionally, NAD may support the body's natural detoxification processes, which are important for maintaining overall health and wellness.

Does NAD improve brain health and function?

NAD is believed to have potential benefits for brain health and function, although more research is needed to fully understand its effects. Some studies have suggested that NAD may have neuroprotective effects, meaning that it may help to protect the brain from damage and support healthy brain function. Additionally, NAD may support the production of neurotransmitters, which are chemicals that help to transmit signals between the brain's cells, and may help to improve cognitive function and memory.